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TVIS30015149
Basic Information
VIS ID
TVIS30015149
Fusion event
HIV-TBC1D2B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
78336567/78044225 (Hg38)
End
78336402/78044225 (Hg38)
Orient
-
Location type
Intronic
Target gene
TBC1D2B
miRNAs that regulate target gene
hsa-mir-7-5p
;
hsa-mir-26b-5p
;
hsa-mir-484
;
hsa-mir-3915
;
hsa-mir-6739-5p
;
hsa-mir-6733-5p
;
hsa-mir-3153
;
hsa-mir-4668-5p
;
hsa-mir-3202
;
hsa-mir-3928-3p
;
hsa-mir-5093
;
hsa-mir-194-3p
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-7843-5p
;
hsa-mir-6879-5p
;
hsa-mir-6735-5p
;
hsa-mir-4632-5p
;
hsa-mir-4436b-3p
;
hsa-mir-6876-5p
;
hsa-mir-4476
;
hsa-mir-1252-3p
;
hsa-mir-6890-3p
;
hsa-mir-603
;
hsa-mir-8485
Nearest miRNA
hsa-mir-10393/Upstream/2281910; hsa-mir-11181/Downstream/1165563;
Nearest TSS
ENST00000557528/Upstream/18597;
ENST00000409568/Downstream/9776;
Nearest CpG islands
None/Target,
chr15-CpG: 55/Upstream/99483
,
chr15-CpG: 103/Downstream/32950
Upstream sequence
gaaatgagaaggaactgctaatgtaatgagtttctttttggatcgatgaaaacatttaaaaattgattgtggtgatggaagcacaactctgtgaatatac
Downstream sequence
caaaaatcattgaattgtacattttaaatgggtgaattgtacagtgtgtgaattgtatatcaataaagttcttctttaaaaaaCAAGTCAACCATAgtgg
Target sequence
tagagatagaaagttgattaggagttgcctacggctgagggttgacagaggagaaggggttgggggaaatgagaaggaactgctaatgtaatgagtttctttttggatcgatgaaaacatttaaaaattgattgtggtgatggaagcacaactctgtgaatatac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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