Basic Information
VIS ID
TVIS30015154
Fusion event
HIV-FANCI integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
89815068/89271837 (Hg38)
End
89815270/89271837 (Hg38)
Orient
+
Location type
Intronic
Target gene
FANCI
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-1-3p ; hsa-mir-192-5p ; hsa-mir-21-5p ; hsa-mir-505-3p ; hsa-let-7c-5p
Nearest miRNA
hsa-mir-10393/Upstream/659903; hsa-mir-1302-10/Downstream/54902;
Nearest TSS
ENST00000557528/Upstream/8400; ENST00000564350/Downstream/6850;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/27377, chr15-CpG: 51/Downstream/61322
Upstream sequence
gcctcctgagtagctgggattacaggtgtgagctaccatatcaggctcatttctttttattgttgaatagtattccattgtgtggatatatatgagtttt
Downstream sequence
cggtatcattttacattcccactatcactatgtgagggttcctatttctctgtgtcttggccaacatttgttattgtctgtcttttttattatatccatt
Target sequence
gtttagcagtctcccagctggtggacatttgaattgtttctactgtttggctattacaaataatgctgccactaacattcaaatgtaagtctttgtgtggacatacattttatttcttttgtgcatatatccaggagtagaactgctggcttatatgagaaatttatgtttatatttttaagaaactgcctgttttccaaaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate