Basic Information
VIS ID
TVIS30015164
Fusion event
HIV-RAB11FIP3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
482969/432969 (Hg38)
End
482915/432969 (Hg38)
Orient
-
Location type
Intronic
Target gene
RAB11FIP3
miRNAs that regulate target gene
hsa-mir-484 ; hsa-mir-1277-5p ; hsa-mir-6516-3p ; hsa-mir-190a-3p ; hsa-mir-3607-5p ; hsa-mir-205-3p ; hsa-mir-5011-5p ; hsa-mir-5580-3p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-4789-5p ; hsa-mir-4672 ; hsa-mir-6768-5p
Nearest miRNA
hsa-mir-6859-4/Upstream/415850; hsa-mir-11401/Downstream/102347;
Nearest TSS
ENST00000527434/Upstream/6590; ENST00000483002/Downstream/41881;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/6154, chr16-CpG: 16/Downstream/49498
Upstream sequence
ctgggattacaggcatgagccattgcccctagccTGAGCTGtttctttttaattgatagaaatatttgtacatattcatgggatgggtacatgtggtatt
Downstream sequence
ttgttacaggcatacactgtaatgatcaagttggggtgtctgtcacctccatatttatctttttttttttttttttttttttgagacatagtctctgtct
Target sequence
ttttaattgatagaaatatttgtacatattcatgggatgggtacatgtggtatt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate