Basic Information
VIS ID
TVIS30015165
Fusion event
HIV-chr16 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
575296/525296 (Hg38)
End
574842/525296 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-6859-4/Upstream/508177; hsa-mir-11401/Downstream/10020;
Nearest TSS
ENST00000527434/Upstream/14733; ENST00000568402/Downstream/2111;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/9515, chr16-CpG: 218/Downstream/1429
Nearby gene
RAB11FIP3(-2811) ; LINC00235(+1551) ;
Upstream sequence
tgttgcccaggctggtGGTCCGTCGTCTTTTTGACCCAGGCCTGTGTGGCTCACAAAGCAGGCAATTGCAGGGTCATCCCATCAAATCTGAGCATGGCAC
Downstream sequence
CAGAGCACACAAGTCAGCCACCTGCGGGCCTTGGCACCCTCGTGCTCCACGCCAGGGTCCCTGTGTGCTCAAGTCTGGGCTCCATGATGGCACTGGGGTT
Target sequence
TCTGCTGAAGGGCAGGTATAGGAAGTCTGGACCCCCTCAGCGGCCCCCCGGATGGCACCCTGGCCCCTCTACCTGCTGGCAGTCCAGTAACCTGGAGGTGGTGGCCCAGAGAAAGGCGGGAACTTCTCCCAGGGCCCCGTCCATTGTTATTTTCACCTGTCCGGCCGCCCAttctttttttgagacggactcagtcacccaggctggagcgccatgtgccatcccagctcactgcagcctcaacctcccgggctc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate