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TVIS30015166
Basic Information
VIS ID
TVIS30015166
Fusion event
HIV-CAPN15 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
583593/533593 (Hg38)
End
583631/533593 (Hg38)
Orient
+
Location type
Intronic
Target gene
CAPN15
miRNAs that regulate target gene
hsa-mir-7-5p
;
hsa-mir-98-5p
;
hsa-let-7d-3p
;
hsa-mir-671-5p
;
hsa-mir-615-3p
;
hsa-mir-92b-3p
;
hsa-mir-193b-3p
;
hsa-mir-484
;
hsa-mir-331-3p
;
hsa-mir-320a
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-92a-2-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-142-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-608
;
hsa-mir-4447
;
hsa-mir-4469
;
hsa-mir-4472
;
hsa-mir-4651
;
hsa-mir-5590-3p
;
hsa-mir-6751-5p
;
hsa-mir-6752-5p
;
hsa-mir-6756-5p
;
hsa-mir-6766-5p
;
hsa-mir-6796-5p
;
hsa-mir-6803-5p
;
hsa-mir-6842-5p
;
hsa-mir-6867-3p
;
hsa-mir-7110-5p
;
hsa-mir-1321
;
hsa-mir-4270
;
hsa-mir-4441
;
hsa-mir-4739
;
hsa-mir-4756-5p
;
hsa-mir-6754-5p
;
hsa-mir-6878-3p
;
hsa-mir-6883-5p
;
hsa-mir-486-3p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-6744-3p
;
hsa-mir-4757-5p
;
hsa-mir-423-5p
;
hsa-mir-3184-5p
;
hsa-mir-3176
;
hsa-mir-3922-3p
;
hsa-mir-140-3p
;
hsa-mir-6743-5p
;
hsa-mir-4688
;
hsa-mir-6742-5p
;
hsa-mir-3151-5p
;
hsa-mir-491-5p
;
hsa-mir-4685-3p
;
hsa-mir-6835-5p
;
hsa-mir-4287
;
hsa-mir-7113-3p
;
hsa-mir-4796-3p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-1200
;
hsa-mir-1207-5p
;
hsa-mir-149-5p
;
hsa-mir-185-3p
;
hsa-mir-24-3p
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-3064-5p
;
hsa-mir-3126-5p
;
hsa-mir-3909
;
hsa-mir-3918
;
hsa-mir-4284
;
hsa-mir-4324
;
hsa-mir-4485-5p
;
hsa-mir-4492
;
hsa-mir-4498
;
hsa-mir-4508
;
hsa-mir-4707-3p
;
hsa-mir-4736
;
hsa-mir-4763-3p
;
hsa-mir-4781-5p
;
hsa-mir-4794
;
hsa-mir-5001-5p
;
hsa-mir-513a-5p
;
hsa-mir-5186
;
hsa-mir-544b
;
hsa-mir-6132
;
hsa-mir-615-5p
;
hsa-mir-6504-5p
;
hsa-mir-664a-5p
;
hsa-mir-6780a-3p
;
hsa-mir-6781-5p
;
hsa-mir-6836-5p
;
hsa-mir-6852-3p
;
hsa-mir-6856-3p
;
hsa-mir-6875-5p
;
hsa-mir-6877-5p
;
hsa-mir-7150
;
hsa-mir-744-5p
;
hsa-mir-762
;
hsa-mir-7845-5p
Nearest miRNA
hsa-mir-6859-4/Upstream/516474; hsa-mir-11401/Downstream/1723;
Nearest TSS
ENST00000527434/Upstream/5737;
ENST00000568402/Downstream/3269;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/5082
,
chr16-CpG: 47/Downstream/4058
Upstream sequence
GCCTGCCCAAGCTGGGCACCTTTCCCTGGCAGTGCCTGGGAAGCTCGGCCGCCCTCCCTGGCTGGTGCTGCTCTGCAGCCCCGCTCATGGACTCTTGCCC
Downstream sequence
TCCGGACAGGATCTTGAATGGCCCTGTCTGCGGTCCTGGCTGGCCGGAGGTTGACCGCACTGGACAGGTCAAGGGCCTTAAACCAGGGTAGTGAGGAGCC
Target sequence
ACGGCCTGCTCCTTGTAGCAGGGTCGGGCCGTGGGAGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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