Basic Information
VIS ID
TVIS30015167
Fusion event
HIV-WDR90 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
708572/658572 (Hg38)
End
708449/658572 (Hg38)
Orient
-
Location type
Exonic
Target gene
WDR90
Nearest miRNA
hsa-mir-3176/Upstream/115206; hsa-mir-11401/Downstream/111611;
Nearest TSS
ENST00000527434/Upstream/12; ENST00000550739/Downstream/673;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/6535, chr16-CpG: 16/Downstream/2493
Upstream sequence
CTGCTGGCCACTCTCCTGAGACACGGCATTTCCCAAGAGCACTGTGTTCCAGCTGCCCGGTGTCCACCCTGAGCCCTGCCCCTCCTTGACGCTCAGTGAG
Downstream sequence
GACGCCCGCTTCCTGCTGATTGCCGCCGGCCGGACCATCAAGGTGTGGGACTACGCCACACAGGCCAGCCCAGGCCCCCAGGTGTGTGCGTGGGGAGGCA
Target sequence
CCACAACGAAGGGAGGCCCCAGGCTGCTGGCCACTCTCCTGAGACACGGCATTTCCCAAGAGCACTGTGTTCCAGCTGCCCGGTGTCCACCCTGAGCCCTGCCCCTCCTTGACGCTCAGTGAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate