Basic Information
VIS ID
TVIS30015170
Fusion event
HIV-IFT140 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
1589240/1539239 (Hg38)
End
1589144/1539239 (Hg38)
Orient
-
Location type
Intronic
Target gene
IFT140
miRNAs that regulate target gene
hsa-mir-93-3p ; hsa-mir-6874-5p ; hsa-mir-6500-5p ; hsa-mir-4633-3p ; hsa-mir-6080 ; hsa-mir-558 ; hsa-mir-6849-5p ; hsa-mir-3681-5p ; hsa-mir-22-3p
Nearest miRNA
hsa-mir-3176/Upstream/768962; hsa-mir-11401/Downstream/195746;
Nearest TSS
ENST00000527434/Upstream/5666; ENST00000563162/Downstream/24871;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1341, chr16-CpG: 22/Downstream/2573
Upstream sequence
cgcctcaggcctcaccaagctgcacagtgccacgccgccccacgccttgggcctcaccaagccacacggtgccaacgccgacccaagcctcaggactcac
Downstream sequence
caagccacacggtgccaagccaccccacaccttgggcctcaccaagccgcacagtgccaGTGACGTCCCATGCCTTGGGCCTCAGCAAGCCACATGGTGC
Target sequence
tcaggcctcaccaagctgcacagtgccacgccgccccacgccttgggcctcaccaagccacacggtgccaacgccgacccaagcctcaggactcac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate