Basic Information
VIS ID
TVIS30015175
Fusion event
HIV-RAB26 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2202409/2152408 (Hg38)
End
2202141/2152408 (Hg38)
Orient
-
Location type
Intronic
Target gene
RAB26
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-421
Nearest miRNA
hsa-mir-1225/Upstream/16279; hsa-mir-11401/Downstream/118305;
Nearest TSS
ENST00000527434/Upstream/832; ENST00000566724/Downstream/634;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/3280, chr16-CpG: 77/Downstream/2798
Upstream sequence
ctgaggttgcagtgagccaagactgtgctacggcactccagcctggacaacagagcaaaactgtctcaaaaaaataaaaTGggctgggcatggtggctca
Downstream sequence
cacctgtaatcccaccaccttgggaggctgaggtgggcggatcacgaggtcaggagttggagaccagcctgatcaacatggtgaaaccccgtctctacta
Target sequence
GGGGGTTATCACTTCTAAAGACAGGTATCCTGGCCAGGCATggcggctcacctgaggtcaggagttcgagaccagcctggccaacatgaggaaaccccatctctactaaaaatacaaaaattagccgggcgttttggcacacacctgtaatcccagctactcaggagactgaggttgcagtgagccaagactgtgctacggcactccagcctggacaacagagcaaaactgtctcaaaaaaataaaaTGggctgg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate