Basic Information
VIS ID
TVIS30015177
Fusion event
HIV-KCTD5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
2757985/2707984 (Hg38)
End
2758046/2707984 (Hg38)
Orient
+
Location type
Exonic
Target gene
KCTD5
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-92a-3p ; hsa-mir-26a-5p ; hsa-mir-125a-3p ; hsa-mir-134-5p ; hsa-mir-155-5p ; hsa-mir-583 ; hsa-mir-1255a ; hsa-mir-1255b-5p ; hsa-mir-3118 ; hsa-mir-3128 ; hsa-mir-3605-5p ; hsa-mir-6894-5p ; hsa-mir-4470 ; hsa-mir-3135a ; hsa-mir-873-5p ; hsa-mir-6089 ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-449c-5p ; hsa-mir-34b-5p ; hsa-mir-2682-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-34a-3p ; hsa-mir-5008-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-3194-3p ; hsa-mir-3607-3p ; hsa-mir-3686 ; hsa-mir-5096 ; hsa-mir-5691 ; hsa-mir-6767-5p ; hsa-mir-6805-3p ; hsa-mir-7974
Nearest miRNA
hsa-mir-1225/Upstream/175979; hsa-mir-11401/Downstream/777397;
Nearest TSS
ENST00000527434/Upstream/22370; ENST00000574340/Downstream/7581;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/74, chr16-CpG: 28/Downstream/7634
Upstream sequence
CCGAGGCCGGGCCTTCTTCTGACACGGGCTCCAACCCCACCTGACCAAGCCCGGGACAGTCAAGGCTTCTCAATTTGTATTTTCCAGGCAAGAGAACTTT
Downstream sequence
TTGCCGCGTGGAGACTGATCTGTTCCATCCGTTAGCGCGAGGTAGCAGTGTCGCCTCGCCCCTCCCACTGCGGGCTCACGGGGAGCTGGCGTCTGTCAGT
Target sequence
GTACCCCTTCTCTGTGTGGATAGACTCCCCAGCGTTTTTCCTCTGGAAATGCCCACAGGGC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate