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TVIS30015188
Basic Information
VIS ID
TVIS30015188
Fusion event
HIV-ADCY9 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.3
Reference genome
GRCh37/hg19
Start
4094604/4044603 (Hg38)
End
4094401/4044603 (Hg38)
Orient
-
Location type
Intronic
Target gene
ADCY9
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-124-3p
;
hsa-mir-7-5p
;
hsa-mir-98-5p
;
hsa-let-7d-5p
;
hsa-mir-877-3p
;
hsa-mir-744-5p
;
hsa-mir-33b-5p
;
hsa-mir-331-3p
;
hsa-mir-10a-5p
;
hsa-mir-99a-5p
;
hsa-mir-181b-5p
;
hsa-mir-143-5p
;
hsa-mir-3944-5p
;
hsa-mir-6870-5p
;
hsa-mir-7111-5p
;
hsa-mir-5698
;
hsa-mir-4723-5p
;
hsa-mir-939-5p
;
hsa-mir-1343-5p
;
hsa-mir-6827-5p
;
hsa-mir-3656
;
hsa-mir-6722-3p
;
hsa-mir-1909-3p
;
hsa-mir-6836-5p
;
hsa-mir-6132
;
hsa-mir-6798-5p
;
hsa-mir-1225-3p
;
hsa-mir-6794-5p
;
hsa-mir-4716-3p
;
hsa-mir-3943
;
hsa-mir-1277-5p
;
hsa-mir-190a-3p
;
hsa-mir-3201
;
hsa-mir-4791
;
hsa-mir-8076
;
hsa-mir-1246
;
hsa-mir-5011-5p
;
hsa-mir-410-3p
;
hsa-mir-6516-5p
;
hsa-mir-29b-2-5p
;
hsa-mir-5047
;
hsa-mir-1301-3p
;
hsa-mir-7156-3p
;
hsa-mir-4436b-5p
;
hsa-mir-185-3p
;
hsa-mir-4656
;
hsa-mir-4448
;
hsa-mir-4660
;
hsa-mir-3177-3p
;
hsa-mir-4508
;
hsa-mir-3189-3p
;
hsa-mir-212-5p
;
hsa-mir-6736-3p
;
hsa-mir-181a-5p
;
hsa-mir-181c-5p
;
hsa-mir-181d-5p
;
hsa-mir-3671
;
hsa-mir-4262
;
hsa-mir-4789-5p
;
hsa-mir-5004-5p
;
hsa-mir-607
;
hsa-mir-6825-5p
;
hsa-mir-7106-5p
;
hsa-mir-7154-3p
Nearest miRNA
hsa-mir-1225/Upstream/559134; hsa-mir-11401/Downstream/626715;
Nearest TSS
ENST00000527434/Upstream/12591;
ENST00000262366/Downstream/9587;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/65191
,
chr16-CpG: 271/Downstream/70204
Upstream sequence
ACTTACATTTTGGAGATCTGGATTTCTCCATTATAAACCTATGGAATCAAATCATTTAAAATCTAGTTACCAGAGAAACCTCGGTTTAATATTAACAAAC
Downstream sequence
ATACTTCCTTTAACCACGAGCCACTTTAATGTATATCAGTTTTATCTCTGGAGCTTCATAGATCCCAACAGAGAAGGCTGATCTATTTTCAGAGAAACAT
Target sequence
TGAAGTAAATAATAAAATTCTGTGATAGGACGGAGCCATTTTCTTCCAGGCTATTTACCAAACACAGCAAAGGAAATCAAAAAAAGGCTTCCCATATAGTAAAACTTACATTTTGGAGATCTGGATTTCTCCATTATAAACCTATGGAATCAAATCATTTAAAATCTAGTTACCAGAGAAACCTCGGTTTAATATTAACAAAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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