Basic Information
VIS ID
TVIS30015189
Fusion event
HIV-RMI2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.13
Reference genome
GRCh37/hg19
Start
11444836/11350979 (Hg38)
End
11444787/11350979 (Hg38)
Orient
-
Location type
Exonic
Target gene
RMI2
miRNAs that regulate target gene
hsa-mir-4480 ; hsa-mir-573 ; hsa-mir-3616-5p ; hsa-mir-3190-3p ; hsa-mir-4795-5p ; hsa-mir-548at-5p
Nearest miRNA
hsa-mir-1225/Upstream/44452; hsa-mir-11401/Downstream/1369342;
Nearest TSS
ENST00000527434/Upstream/1658; ENST00000572950/Downstream/32726;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/5069, chr16-CpG: 31/Downstream/142784
Upstream sequence
GCGTATTTTTCAAATGCTTCTCAGAGAGCCTTGCTTTGGTTGACCAAGGAGTCCGGATGTAGGAATGTTTAAATCCTCGGATACTTCAGTGACACAGCCT
Downstream sequence
CTGCTGCCCCTTGCTTTGCCTGTGTTTGCTGATGAAAAGCAGATGCTTGTGTTTCATTTTCCTTCCTGGTTTGTGTGTGTTAATTCTCTCTCTCTCTCTC
Target sequence
TCCGGATGTAGGAATGTTTAAATCCTCGGATACTTCAGTGACACAGCCT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate