Basic Information
VIS ID
TVIS30015224
Fusion event
HIV-MRTFB integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.12
Reference genome
End
14307816/14213776 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/1493405; hsa-mir-11401/Downstream/90191;
Nearest cancer related gene
MRTFB(OG, No orient, 0)
Upstream sequence
TTTCCACCATTTCTGTTTATTCCCATTTTAATAACTTTTTAACCCACAGCCTTACTTCCTCCAAACTGGATAGCAACATGAAGACCCAAAACTAAAACAT
Downstream sequence
AAGTCTAACCCTAGATTTTCAACTACTTGGACCTTGTCTGTGTCTAACTGTACAGTGCCCACACCCAACATTTTCTCTTTATTGCCACTTACCCACAACA
Target sequence
GTTAGATACACAGGGAAGGTTTGATTCTTCACATAACCAATTAATGGACTAACACTTCCACACCAGCTGGTACCACAGATGCCTCTACCATACTGTTCCACTAAAAAAATTGGGGTCCAGAGGATTTCTTTATCAGTGAGGGACATGTATCCACTTATTAAGTCATAAAGAATGCAATAGCAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate