Basic Information
VIS ID
TVIS30015302
Fusion event
HIV-MRTFB integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.12
Reference genome
End
14310321/14216543 (Hg38)
Orient
-
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/1496172; hsa-mir-11401/Downstream/87424;
Nearest cancer related gene
MRTFB(OG, No orient, 0)
Upstream sequence
CAGATGGATGAATTATGGTATTTATAGTTTTACATTGGTTGTACCAATTTTATGCATTTGTAAGTAGATGAGTTGATGCCTGTATACAACCATTAATTAC
Downstream sequence
TGTATATTATAGTTGAATGTTCCTAACAGACACAAGGATATGTATTCAGAAATAAACCCAAATTCTTAATTATGATGACCGACCGAGACACAGGGGATCA
Target sequence
TTATAGTTTTACATTGGTTGTACCAATTTTATGCATTTGTAAGTAGATGAGTTGATGCCTGTATACAACCATTAATTAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate