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Viral Integration Site DataBase
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TVIS30015319
Proximate region of VIS (GRCh38)
VIS
Enhancer
Enhancer/Promoter
Promoter
Gene
18730004
18804853
18926454
18788063
18801519
18791667
18801678
18797463
18807179
18803083
18812181
18781295
18790383
18786475
18791478
18828025
18830486
18780124
18782389
18818940
18820280
18783844
18784289
18783119
18783268
18785619
18785768
18793179
18793328
18796539
18796688
18828229
Basic Information
VIS ID
TVIS30015319
Fusion event
HIV-SMG1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
18839551/18828229 (Hg38)
End
18839405/18828229 (Hg38)
Orient
-
Location type
Intronic
Target gene
SMG1
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-877-5p
;
hsa-mir-615-3p
;
hsa-mir-92b-3p
;
hsa-mir-361-5p
;
hsa-mir-181a-5p
;
hsa-mir-106a-5p
;
hsa-mir-100-5p
;
hsa-mir-17-3p
;
hsa-let-7b-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-3184-3p
;
hsa-mir-6890-3p
;
hsa-mir-4709-5p
;
hsa-mir-4740-5p
;
hsa-mir-4267
;
hsa-mir-891a-3p
;
hsa-mir-1256
;
hsa-mir-142-3p
;
hsa-mir-6515-5p
;
hsa-mir-6739-5p
;
hsa-mir-6733-5p
;
hsa-mir-3153
;
hsa-mir-1273a
;
hsa-mir-31-5p
;
hsa-mir-6797-5p
;
hsa-mir-1249-5p
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-5681a
;
hsa-mir-6847-5p
;
hsa-mir-4802-5p
;
hsa-mir-548aw
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-4795-3p
;
hsa-mir-6499-3p
;
hsa-mir-1468-3p
;
hsa-mir-548x-5p
;
hsa-mir-548g-5p
;
hsa-mir-548f-5p
;
hsa-mir-548aj-5p
;
hsa-mir-4302
;
hsa-mir-126-5p
;
hsa-mir-183-5p
;
hsa-mir-4666a-3p
;
hsa-mir-648
;
hsa-mir-4519
;
hsa-mir-338-5p
;
hsa-mir-5583-3p
;
hsa-mir-559
;
hsa-mir-548y
;
hsa-mir-548w
;
hsa-mir-548o-5p
;
hsa-mir-548j-5p
;
hsa-mir-548i
;
hsa-mir-548h-5p
;
hsa-mir-548d-5p
;
hsa-mir-548c-5p
;
hsa-mir-548bb-5p
;
hsa-mir-548b-5p
;
hsa-mir-548ay-5p
;
hsa-mir-548au-5p
;
hsa-mir-548as-5p
;
hsa-mir-548ar-5p
;
hsa-mir-548aq-5p
;
hsa-mir-548ap-5p
;
hsa-mir-548am-5p
;
hsa-mir-548ak
;
hsa-mir-548ae-5p
;
hsa-mir-548ad-5p
;
hsa-mir-548ab
;
hsa-mir-548a-5p
;
hsa-mir-4422
;
hsa-mir-4282
;
hsa-mir-6835-3p
;
hsa-mir-548n
;
hsa-mir-539-5p
;
hsa-mir-545-5p
;
hsa-mir-330-3p
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-4311
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-8070
;
hsa-mir-6842-3p
;
hsa-mir-647
;
hsa-mir-502-5p
;
hsa-mir-4687-3p
;
hsa-mir-7974
;
hsa-mir-4679
;
hsa-mir-3189-3p
;
hsa-mir-4762-5p
;
hsa-mir-141-5p
;
hsa-mir-212-5p
;
hsa-mir-510-3p
;
hsa-mir-488-3p
;
hsa-mir-3169
;
hsa-mir-4662b
;
hsa-mir-4647
;
hsa-mir-4426
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-548t-5p
;
hsa-mir-548az-5p
;
hsa-mir-5698
;
hsa-mir-143-5p
;
hsa-mir-4430
;
hsa-mir-3652
;
hsa-mir-4284
;
hsa-mir-122-5p
;
hsa-mir-504-3p
;
hsa-mir-3135b
;
hsa-mir-2276-3p
;
hsa-mir-4638-5p
;
hsa-mir-1307-3p
;
hsa-mir-6741-3p
;
hsa-mir-1304-3p
;
hsa-mir-4485-5p
;
hsa-mir-5693
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-1193
;
hsa-mir-6845-3p
;
hsa-mir-6812-3p
;
hsa-mir-2392
;
hsa-mir-575
;
hsa-mir-4676-5p
;
hsa-mir-6858-3p
;
hsa-mir-32-5p
;
hsa-mir-92a-3p
;
hsa-mir-3125
;
hsa-mir-3916
;
hsa-mir-5584-5p
;
hsa-mir-6859-5p
Nearest miRNA
hsa-mir-1225/Upstream/333653; hsa-mir-11401/Downstream/2677820;
Nearest TSS
ENST00000527434/Upstream/12050;
ENST00000565782/Downstream/21141;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/26152
,
chr16-CpG: 119/Downstream/97479
Upstream sequence
GGCTTGTGGTCTATTGATAAGTAGATCTTCATGTTGCCACTGTTGAGAGAAAAAGAAATGTATTAAAATCAGCAGGAAAAAAGCGTTTAGATAAATAAGG
Downstream sequence
GAAGGGAGGCGCAACCTAGGACTGGCGGAAGAGAAAAAAATCCCAGCTGCAGCCAATGGGAGGTAAGCAGGGAGAAGTAACAGAAAAGACACACTGAAAA
Target sequence
TCATGCTGGTTAGGATAGCAGACCGTGGGGGAGGTGTGACTGACATGGCTTGTGGTCTATTGATAAGTAGATCTTCATGTTGCCACTGTTGAGAGAAAAAGAAATGTATTAAAATCAGCAGGAAAAAAGCGTTTAGATAAATAAGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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