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TVIS30015322
Basic Information
VIS ID
TVIS30015322
Fusion event
HIV-GGA2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
23475831/23464510 (Hg38)
End
23475911/23464510 (Hg38)
Orient
+
Location type
Exonic
Target gene
GGA2
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-24-3p
;
hsa-mir-92a-3p
;
hsa-mir-26a-5p
;
hsa-mir-5089-5p
;
hsa-mir-6807-5p
;
hsa-mir-5589-5p
;
hsa-mir-4731-5p
;
hsa-mir-4252
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-150-5p
;
hsa-mir-186-3p
;
hsa-mir-4698
;
hsa-mir-1295b-3p
;
hsa-mir-3186-5p
;
hsa-mir-3682-3p
;
hsa-mir-4770
;
hsa-mir-6088
;
hsa-mir-143-3p
;
hsa-mir-539-5p
;
hsa-mir-4756-3p
;
hsa-mir-1272
;
hsa-mir-5680
;
hsa-mir-383-5p
;
hsa-mir-3607-3p
;
hsa-mir-499b-5p
;
hsa-mir-4494
;
hsa-mir-548c-3p
;
hsa-mir-6501-3p
;
hsa-mir-8485
;
hsa-mir-298
;
hsa-mir-17-3p
;
hsa-mir-1205
;
hsa-mir-1184
;
hsa-mir-3158-5p
;
hsa-mir-7977
;
hsa-mir-675-5p
;
hsa-mir-4466
;
hsa-mir-4746-3p
;
hsa-mir-6089
;
hsa-mir-4284
;
hsa-mir-4672
;
hsa-mir-6768-5p
;
hsa-mir-548s
;
hsa-mir-3926
;
hsa-mir-4786-5p
;
hsa-mir-3190-5p
;
hsa-mir-7162-3p
;
hsa-mir-5699-3p
;
hsa-mir-4421
;
hsa-mir-6748-3p
;
hsa-mir-544b
;
hsa-mir-6849-3p
;
hsa-mir-4433a-3p
;
hsa-mir-4459
;
hsa-mir-4768-3p
;
hsa-mir-6765-3p
;
hsa-mir-224-5p
Nearest miRNA
hsa-mir-1225/Upstream/1958375; hsa-mir-11401/Downstream/738606;
Nearest TSS
ENST00000527434/Upstream/11330;
ENST00000566669/Downstream/2903;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/11202
,
chr16-CpG: 29/Downstream/45749
Upstream sequence
CAACTTGAATTTGATCCCATAAAGTCAGGCATCAGGAAGCCATTCAGAATTTTTCACCCTGTCAGATGCTCAGATTTGCTAGAGAACTCTGGTAGTGGCA
Downstream sequence
TAAGTGCAGGGAGGACATGATGTGGGATTATTTAGAAAACAGGCCAAATGACATGCAACTACTCTGCGGATACAGACGAAGCAGGAATCAGGGACCCAAT
Target sequence
AGAACCAGAGCTGTTACTCAGAATTGGGACAGAGGCATTGTCCCAAAAAAAAAAAAGCCCAAATCAGAGCAGTGGCAATG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT4
Sample type
PBMC
Age
39
Gender
Male
CpG Island Information
×
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