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TVIS30015328
Basic Information
VIS ID
TVIS30015328
Fusion event
HIV-PRKCB integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
24144986/24133665 (Hg38)
End
24144811/24133665 (Hg38)
Orient
-
Location type
Intronic
Target gene
PRKCB
miRNAs that regulate target gene
hsa-mir-124-3p
;
hsa-mir-142-5p
;
hsa-mir-3650
;
hsa-mir-4796-3p
;
hsa-mir-5590-3p
;
hsa-mir-6867-5p
;
hsa-mir-1261
;
hsa-mir-3614-5p
;
hsa-mir-381-3p
;
hsa-mir-300
;
hsa-mir-890
;
hsa-mir-574-5p
;
hsa-mir-4455
;
hsa-mir-4999-5p
;
hsa-mir-4718
;
hsa-mir-1537-5p
;
hsa-mir-4742-3p
;
hsa-mir-93-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-20b-5p
;
hsa-mir-20a-5p
;
hsa-mir-17-5p
;
hsa-mir-106b-5p
;
hsa-mir-106a-5p
;
hsa-mir-548ah-5p
;
hsa-mir-3609
;
hsa-mir-6868-3p
;
hsa-mir-627-3p
;
hsa-mir-1248
;
hsa-mir-3667-3p
;
hsa-mir-6734-3p
;
hsa-mir-6074
;
hsa-mir-4753-3p
;
hsa-mir-6809-3p
;
hsa-mir-130b-5p
;
hsa-mir-3180-5p
;
hsa-mir-6780a-3p
;
hsa-mir-6881-3p
;
hsa-mir-525-5p
;
hsa-mir-520a-5p
;
hsa-mir-877-3p
;
hsa-mir-488-5p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-4778-3p
;
hsa-mir-184
;
hsa-mir-33a-5p
Nearest miRNA
hsa-mir-1225/Upstream/2627530; hsa-mir-11401/Downstream/69451;
Nearest TSS
ENST00000527434/Upstream/98130;
ENST00000463752/Downstream/18020;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/296884
,
chr16-CpG: 44/Downstream/122054
Nearest cancer related gene
PRKCB
(TSG, No orient, 0)
Upstream sequence
TTAACCCTTACCAACTCTACTGCCCAGCTGCACCCACTCCAATTCCACTCACACCCTGCCCATTATCgccaacgtttctgagctcatgctcattgacaag
Downstream sequence
gaccatgccatggatttgcatgcattatatcatattaattcacaccataatcctgcaaggtagtcactgataatcactctattatatcatatagaaattg
Target sequence
CAAGTCTTGGAAGCATCTCTAGTGAGTGCAGTGACTCCTTAGCTGGTTCCTTTTCAACCTTCAACCTCCATTTTCTTAACCCTTACCAACTCTACTGCCCAGCTGCACCCACTCCAATTCCACTCACACCCTGCCCATTATCgccaacgtttctgagctcatgctcattgacaag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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