Basic Information
VIS ID
TVIS30015333
Fusion event
HIV-chr16 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
30611843/30600522 (Hg38)
End
30611478/30600522 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1225/Upstream/96521; hsa-mir-11401/Downstream/274744;
Nearest TSS
ENST00000527434/Upstream/14615; ENST00000563211/Downstream/8963;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/14972, chr16-CpG: 48/Downstream/3934
Nearby gene
ZNF689(No orient, 2856)
Upstream sequence
TGGTCAATTTGGAGTCACAGCAGGGAGACTCATGGAGGAGTGTCTGTtaacacctactttatagagttcttgtgaacattggattggaatgtatataaag
Downstream sequence
tgcctaacacagtacatggaacatcataaaagctcagtcaagtggctattaatattGCAGTAGGCCAAAGAATAAACAGAAGTGGATTCAggccaggtgc
Target sequence
taatGTGcttgctaaatggctgcaggtacacttggaaaaggctagaagctctacagcatgtttttgtcagtgtagaactgacatcaagtccttcatcaagggaacccagcctccccagatctagagaaggggagactctagatctgtgaataggctcaagtctgagaatctgttgaaggcagggacttgcaatttttGCCAACTCAACAAGATGTGAAGGCAGGACTTGCCGAGATGGATCGGAAGTCAACATGA
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate