Basic Information
VIS ID
TVIS30015337
Fusion event
HIV-KAT8 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
31131388/31120067 (Hg38)
End
31131254/31120067 (Hg38)
Orient
-
Location type
Intronic
Target gene
KAT8
Nearest miRNA
hsa-mir-1225/Upstream/226082; hsa-mir-11401/Downstream/3043511;
Nearest TSS
ENST00000527434/Upstream/2370; ENST00000573144/Downstream/5517;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/2174, chr16-CpG: 88/Downstream/22168
Upstream sequence
acacacccagccagttattttctcattcgtaaaatgagaataacagcctcaacctgatccacctcacagttgtggcagtgattgagtagaatggcagagg
Downstream sequence
tggaCCAGTGAGGTTAGCTGATGTGTGGCCCTGAACTCTGGAAACTGCTTCTCAGTGTGCAGGATTCCTTTTGTTCCAGCCTTACCTTCCTGATGACCCT
Target sequence
gcctccagaagtactgggattacaggtgtgagccacacacccagccagttattttctcattcgtaaaatgagaataacagcctcaacctgatccacctcacagttgtggcagtgattgagtagaatggcagagg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate