Basic Information
VIS ID
TVIS30015341
Fusion event
HIV-ZNF267 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
31900036/31888715 (Hg38)
End
31899955/31888715 (Hg38)
Orient
-
Location type
Intronic
Target gene
ZNF267
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-98-5p ; hsa-mir-6885-3p ; hsa-mir-510-3p ; hsa-mir-4477b ; hsa-mir-183-3p ; hsa-mir-488-3p ; hsa-mir-6124 ; hsa-mir-190a-3p ; hsa-mir-3160-5p ; hsa-mir-4680-3p ; hsa-mir-410-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-6838-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-651-3p ; hsa-mir-3591-3p ; hsa-mir-21-3p ; hsa-mir-5692a ; hsa-mir-4429 ; hsa-mir-320d ; hsa-mir-320c ; hsa-mir-320b ; hsa-mir-320a ; hsa-mir-548e-5p ; hsa-mir-3064-3p ; hsa-mir-4633-5p ; hsa-mir-154-5p ; hsa-mir-548m ; hsa-mir-6841-3p ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-137 ; hsa-mir-2276-3p ; hsa-mir-4772-3p ; hsa-mir-4729 ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-32-5p ; hsa-mir-25-3p ; hsa-mir-130a-5p ; hsa-mir-23a-3p ; hsa-mir-23b-3p ; hsa-mir-23c
Nearest miRNA
hsa-mir-1225/Upstream/994730; hsa-mir-11401/Downstream/2274863;
Nearest TSS
ENST00000527434/Upstream/14649; ENST00000575471/Downstream/23139;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/14436, chr16-CpG: 30/Downstream/93167
Upstream sequence
atcatttaaattgtgtatgttaaaacattcttgcatctcagggataaatcctacttgataatgatgtctgatccttttaatgtgtttttgaatttggtat
Downstream sequence
ctagtattttgttgagaatttttgcttgtatctttataaggaatattgttttgttacttttttgtagtgtccttatctggcttcagtatgagatgttggt
Target sequence
ttaaaacattcttgcatctcagggataaatcctacttgataatgatgtctgatccttttaatgtgtttttgaatttggtat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate