Basic Information
VIS ID
TVIS30015344
Fusion event
HIV-LONP2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
48316013/48282102 (Hg38)
End
48316142/48282102 (Hg38)
Orient
+
Location type
Intronic
Target gene
LONP2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-505-5p ; hsa-mir-30c-2-3p ; hsa-mir-193b-3p ; hsa-mir-320a ; hsa-mir-1287-5p ; hsa-mir-3135b ; hsa-mir-3692-5p ; hsa-mir-22-3p ; hsa-mir-1182 ; hsa-mir-129-5p ; hsa-mir-1304-3p ; hsa-mir-1915-3p ; hsa-mir-3664-5p ; hsa-mir-3672 ; hsa-mir-4524a-3p ; hsa-mir-4524b-3p ; hsa-mir-4639-3p ; hsa-mir-6764-5p ; hsa-mir-6794-3p ; hsa-mir-6864-3p ; hsa-mir-8055
Nearest miRNA
hsa-mir-1225/Upstream/14118429; hsa-mir-11401/Downstream/2010514;
Nearest TSS
ENST00000527434/Upstream/19326; ENST00000564259/Downstream/52210;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/37358, chr16-CpG: 30/Downstream/83717
Upstream sequence
TATAATTTCCAAATATCGAATGGAGTTAAAAAATGCCTTAAATAaggcataccttgttttattgtgttgtgcttcattgtacttcacagactgtgttttt
Downstream sequence
aaccctgtctctactaaaaacccacaaaaattagctgggcatggtcgtgcatgcctgtaatcccagccactcaggaggctgaggcatgagaatagcttga
Target sequence
ttaacaaattaaatgtttatggcaggccaggcacagtggctcacgcctgtaatcctagcactttgggaggccgaggcgggtggattgcctgagctcaggagttcaagaccagcctggctaacgtggcga
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate