VISDB - VIS Detail

Basic Information

VIS ID

TVIS30015345

Fusion event

HIV-N4BP1 integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

PBMC

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

24968937

Virus Sequence

Virus name

HIV

Reference genome

Not given

Host Sequence

Chromosome

chr16

Cytoband

q12.1

Reference genome

GRCh37/hg19

Start

48592656/48558745 (Hg38)

End

48592761/48558745 (Hg38)

Orient

Location type

Intronic

Target gene

N4BP1

miRNAs that regulate target gene

hsa-mir-28-5p ; hsa-mir-708-3p ; hsa-mir-151a-5p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-320b ; hsa-mir-93-5p ; hsa-mir-190a-3p ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-155-5p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-4696 ; hsa-mir-5094 ; hsa-mir-4645-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4436b-3p ; hsa-mir-4632-5p ; hsa-mir-451b ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-101-3p ; hsa-mir-499b-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-2276-3p ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-6736-3p ; hsa-mir-1228-3p ; hsa-mir-6083 ; hsa-mir-3686 ; hsa-mir-2054 ; hsa-mir-3607-3p ; hsa-mir-646 ; hsa-mir-32-3p ; hsa-mir-6838-5p ; hsa-mir-503-5p ; hsa-mir-497-5p ; hsa-mir-424-5p ; hsa-mir-15a-5p ; hsa-mir-195-5p ; hsa-mir-15b-5p ; hsa-mir-107 ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-1224-5p ; hsa-mir-1262 ; hsa-mir-3173-3p ; hsa-mir-3689d ; hsa-mir-381-5p ; hsa-mir-4701-3p ; hsa-mir-4710 ; hsa-mir-4737 ; hsa-mir-4751 ; hsa-mir-5004-5p ; hsa-mir-513b-5p ; hsa-mir-6736-5p ; hsa-mir-6776-5p ; hsa-mir-6851-5p ; hsa-mir-6891-5p

Nearest miRNA

hsa-mir-1225/Upstream/14395072; hsa-mir-11401/Downstream/1733871;

Nearest TSS

ENST00000527434/Upstream/5092; ENST00000563994/Downstream/916;

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/61847, chr16-CpG: 87/Downstream/251895

Upstream sequence

AAGTGAAAGAGGATGAGAATTGCTCACAATTGTGACCTAAATTTTGTGTCACGAGTTGGCTCAAGAAATCGTAACAATGAAGAACTTGTTCCGGGCTTGG

Downstream sequence

GACAATAAACAGTATTATTTGGAAATGAAGATAAGCATATTGCATATTTTTGCTGCCTGTCTTCAAACTTTAACATCTGAAATGATGACATTTTCTTTTT

Target sequence

GGTGTGGGTGACTGAAGTGACATTTTTGCTTAGATATCGCTATGCAGCTGCGGATCATTTGCTGGGTTTCCCCTAACAGGGCTGCCAAAAAAACCAAAGTGAAAT

Reference

Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.