Basic Information
VIS ID
TVIS30015350
Fusion event
HIV-CYLD integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
End
50818697/50784748 (Hg38)
Orient
+
Location type
Intronic
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/42371; hsa-mir-11401/Downstream/5460772;
Nearest cancer related gene
CYLD(TSG, No orient, 0)
Upstream sequence
GTAGAACATAGCATATTCCATGAAATGATTTAACCTATTTTGCTAGAGTAAACTATAATTTAGCAATTGCAGTATGTTTAGGAAAGCTAATACATAATAC
Downstream sequence
TTCTGCTACAAGTAATCATGCTTATTAGTTAAATTGGTGTAGTCTAGCTTCTTAAATCTGAAAGAAAAGGAGAAAGGGAAATTCTTTATAGAATAGCTAG
Target sequence
TTAGGATTCTTATCTTTTGAAATAGTTTATTCCAACAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate