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TVIS30015350
Basic Information
VIS ID
TVIS30015350
Fusion event
HIV-CYLD integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
50818659/50784748 (Hg38)
End
50818697/50784748 (Hg38)
Orient
+
Location type
Intronic
Target gene
CYLD
miRNAs that regulate target gene
hsa-mir-197-3p
;
hsa-mir-181b-5p
;
hsa-mir-182-5p
;
hsa-mir-320a
;
hsa-mir-362-5p
;
hsa-mir-500a-5p
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-519d-3p
;
hsa-mir-4789-5p
;
hsa-mir-3941
;
hsa-mir-5011-5p
;
hsa-mir-5580-3p
;
hsa-mir-603
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-8485
;
hsa-mir-6833-3p
;
hsa-mir-4768-5p
;
hsa-mir-6873-3p
;
hsa-mir-6740-3p
;
hsa-mir-942-5p
;
hsa-mir-6817-3p
;
hsa-mir-7110-3p
;
hsa-mir-6845-3p
;
hsa-mir-605-5p
;
hsa-mir-384
;
hsa-mir-3685
;
hsa-mir-1200
;
hsa-mir-7975
;
hsa-mir-378a-5p
;
hsa-mir-5571-3p
;
hsa-mir-6744-3p
;
hsa-mir-4757-5p
;
hsa-mir-6781-3p
;
hsa-mir-2682-3p
;
hsa-mir-1236-3p
;
hsa-mir-3140-5p
;
hsa-mir-3142
;
hsa-mir-877-3p
;
hsa-mir-1245b-5p
;
hsa-mir-335-3p
;
hsa-mir-3156-3p
;
hsa-mir-188-3p
;
hsa-mir-7106-5p
;
hsa-mir-765
;
hsa-mir-7154-3p
;
hsa-mir-659-5p
;
hsa-mir-4751
;
hsa-mir-3667-3p
;
hsa-mir-4301
;
hsa-mir-4528
;
hsa-mir-6754-5p
;
hsa-mir-4441
;
hsa-mir-4270
;
hsa-mir-211-3p
;
hsa-mir-4756-5p
;
hsa-mir-1321
;
hsa-mir-4739
;
hsa-mir-195-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-130b-3p
;
hsa-mir-922
;
hsa-mir-126-5p
Nearest miRNA
hsa-mir-1225/Upstream/42371; hsa-mir-11401/Downstream/5460772;
Nearest TSS
ENST00000527434/Upstream/8547;
ENST00000562884/Downstream/8869;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/42030
,
chr16-CpG: 28/Downstream/56404
Nearest cancer related gene
CYLD
(TSG, No orient, 0)
Upstream sequence
GTAGAACATAGCATATTCCATGAAATGATTTAACCTATTTTGCTAGAGTAAACTATAATTTAGCAATTGCAGTATGTTTAGGAAAGCTAATACATAATAC
Downstream sequence
TTCTGCTACAAGTAATCATGCTTATTAGTTAAATTGGTGTAGTCTAGCTTCTTAAATCTGAAAGAAAAGGAGAAAGGGAAATTCTTTATAGAATAGCTAG
Target sequence
TTAGGATTCTTATCTTTTGAAATAGTTTATTCCAACAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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