Basic Information
VIS ID
TVIS30015351
Fusion event
HIV-CHD9 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
53300580/53266668 (Hg38)
End
53300538/53266668 (Hg38)
Orient
-
Location type
Intronic
Target gene
CHD9
miRNAs that regulate target gene
hsa-mir-210-3p ; hsa-mir-155-5p ; hsa-mir-7-5p ; hsa-mir-26b-5p ; hsa-let-7e-5p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-22-3p ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-376a-5p ; hsa-mir-181d-5p ; hsa-mir-376a-2-5p ; hsa-mir-944 ; hsa-mir-664a-3p ; hsa-mir-2052 ; hsa-mir-1193 ; hsa-mir-4262 ; hsa-mir-3607-3p ; hsa-mir-3668 ; hsa-mir-3686 ; hsa-mir-3935 ; hsa-mir-4663 ; hsa-mir-4682 ; hsa-mir-8077 ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-34b-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-6873-3p ; hsa-mir-6794-3p ; hsa-mir-627-3p ; hsa-mir-4639-3p ; hsa-mir-342-3p ; hsa-mir-548c-3p ; hsa-mir-3163 ; hsa-mir-628-5p ; hsa-mir-7641 ; hsa-mir-3171 ; hsa-mir-139-5p
Nearest miRNA
hsa-mir-1225/Upstream/2524291; hsa-mir-11401/Downstream/2978852;
Nearest TSS
ENST00000527434/Upstream/16767; ENST00000564600/Downstream/47838;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/134742, chr16-CpG: 37/Downstream/106747
Upstream sequence
ataaaaaatttcatcccaaatagcatttgtttagtgacacatttgtccgtgtaactaaaactttggattccttatgagtagaaacagccttattcatcat
Downstream sequence
tataccacagcccataacatagtgcctagcttagagaagtttctcaataaaAATAAAAAGTATGTTAACATAAATTGTTTTGAATGAATTAAACTGAATC
Target sequence
aactttggattccttatgagtagaaacagccttattcatcat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate