Basic Information
VIS ID
TVIS30015354
Fusion event
HIV-GNAO1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
GRCh37/hg19
Start
56248982/56215070 (Hg38)
End
56248910/56215070 (Hg38)
Orient
-
Location type
Intronic
Target gene
GNAO1
Nearest miRNA
hsa-mir-1225/Upstream/5472693; hsa-mir-11401/Downstream/30450;
Nearest TSS
ENST00000527434/Upstream/20552; ENST00000563440/Downstream/11309;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/22704, chr16-CpG: 15/Downstream/148842
Upstream sequence
CTGGGCATTGGCTTGGCTTGGAGGACATACCATGGTGTAGTGCACCACACTGATCCTGAGTTGGCTCCCCCTACTACAGAACGCCTTCTCCCTGGCACCC
Downstream sequence
ACCACCTCCTGCCTCCATACCCATAGCTGGTGGCTGCCAAAGCATGCTTCCTCCTCTTTCTCTGTAGATCTGGCCTCCAAGGGCCGCTCAAGTCTCATCT
Target sequence
ACCATGGTGTAGTGCACCACACTGATCCTGAGTTGGCTCCCCCTACTACAGAACGCCTTCTCCCTGGCACCC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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