Basic Information
VIS ID
TVIS30015355
Fusion event
HIV-HERPUD1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
GRCh37/hg19
Start
56971954/56938042 (Hg38)
End
56971895/56938042 (Hg38)
Orient
-
Location type
Intronic
Target gene
HERPUD1
miRNAs that regulate target gene
hsa-mir-373-3p ; hsa-mir-335-5p ; hsa-mir-375 ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-93-5p ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-4451 ; hsa-mir-6499-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-98-5p ; hsa-mir-4458 ; hsa-mir-4500 ; hsa-let-7i-5p ; hsa-let-7g-5p ; hsa-let-7f-5p ; hsa-let-7e-5p ; hsa-let-7d-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-4537 ; hsa-mir-4680-5p ; hsa-mir-3664-3p ; hsa-mir-1292-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-6831-5p ; hsa-mir-3927-3p ; hsa-mir-510-5p ; hsa-mir-203b-3p ; hsa-mir-7158-3p ; hsa-mir-1285-3p ; hsa-mir-196a-3p ; hsa-mir-3187-5p ; hsa-mir-4797-5p ; hsa-mir-508-5p ; hsa-mir-5189-5p ; hsa-mir-5586-3p ; hsa-mir-612 ; hsa-mir-6512-3p ; hsa-mir-661 ; hsa-mir-6720-5p ; hsa-mir-6849-3p ; hsa-mir-6860 ; hsa-mir-759 ; hsa-mir-766-3p ; hsa-mir-939-3p
Nearest miRNA
hsa-mir-1225/Upstream/33689; hsa-mir-11401/Downstream/834247;
Nearest TSS
ENST00000527434/Upstream/1318; ENST00000567944/Downstream/1102;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/5531, chr16-CpG: 54/Downstream/51236
Upstream sequence
ACTTAAAACTACTTCCCTTATTCTGATTCAACTATTCTTAACTTGAGAATTGAGGCTCATATTTGACTCTCTGAATCTCACCATATTTAAACTTGATTTC
Downstream sequence
CTTTAACAAATATTTATTGAACAGCCAGTACATACAACTTTGCTTAAGGATATGAGTTGACCTGCAGGAATGACCACATAACCAATTTCTGATCTTTGGG
Target sequence
CTTGAGAATTGAGGCTCATATTTGACTCTCTGAATCTCACCATATTTAAACTTGATTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate