VISDB Viral Integration Site DataBase

VIS ID

TVIS30015361

Fusion event

HIV-CBFB integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr16

Cytoband

q22.1

Reference genome

Start

End

67098704/67064627 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-145-5p ; hsa-mir-155-5p ; hsa-mir-125b-5p ; hsa-let-7b-5p ; hsa-mir-30a-5p ; hsa-mir-130b-3p ; hsa-mir-615-3p ; hsa-mir-92a-3p ; hsa-mir-5692a ; hsa-mir-100-3p ; hsa-mir-153-3p ; hsa-mir-570-5p ; hsa-mir-624-3p ; hsa-mir-4327 ; hsa-mir-548ag ; hsa-mir-548ai ; hsa-mir-548ba ; hsa-mir-448 ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p

Nearest miRNA

hsa-mir-1225/Upstream/9292275; hsa-mir-11401/Downstream/137694;

Nearest TSS

Nearest CpG islands

None/Target, chr16-CpG: 29/Upstream/34518, chr16-CpG: 79/Downstream/44752

Nearest cancer related gene

CBFB(OG, No orient, 0)

Upstream sequence

ACTATTAGGTTAGTGTGGTATTAGGAGTGGGAAGATTGTAGAAACTGTAATAAATTTCTCTTATATTGTTTATCTCTATCACAATAAAATATTCACCTCA

Downstream sequence

GCAGAAATGGGTTTTTGTTTTTTGTTGTTGTTTTTTATTGTTGTTGTTTCAGAAGAAAAGTTAATAAAAGTGTAAAACAGAAGTTttcttttttttctct

Target sequence

GGATGATAGAATTAACACCGTCCTTTCTGGGTGGATAGTTACTCTTGGGAACAATTGTATTTTGAGCCAATATGAGAATTAATTTGGTGATCAAAAATGATCTAAATTTGGGTATGATGTATACCTAAAGCAATTTTTATTCTAGAGTTATTTATTTACTTGAAAAAGAATGGT