Basic Information
VIS ID
TVIS30015362
Fusion event
HIV-TRADD integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
67191371/67157468 (Hg38)
End
67191250/67157468 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
TRADD
miRNAs that regulate target gene
hsa-mir-5704 ; hsa-mir-4480 ; hsa-mir-338-3p ; hsa-mir-4530 ; hsa-mir-1295b-3p ; hsa-mir-922 ; hsa-mir-15a-3p ; hsa-mir-4717-5p ; hsa-mir-30c-2-3p
Nearest miRNA
hsa-mir-1225/Upstream/9385116; hsa-mir-11401/Downstream/44853;
Nearest TSS
ENST00000527434/Upstream/787; ENST00000518148/Downstream/2430;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/1719, chr16-CpG: 16/Downstream/1634
Upstream sequence
cttaagttggacccatgagaatcaacgctgcgactctggttgagccaataggaaagaggcactactttcccttcccttggggctgaactggaaggaaaag
Downstream sequence
gtagctctcctttagcactgcttgggaagagcctggctgggaatgaagctgacacagaaagaaagagtcaagagatggagaagtgcattcctaagcatac
Target sequence
agttcagggcggggtataggacttaagttggacccatgagaatcaacgctgcgactctggttgagccaataggaaagaggcactactttcccttcccttggggctgaactggaaggaaaag
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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