Basic Information
VIS ID
TVIS30015369
Fusion event
HIV-NFATC3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
End
68130643/68096996 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
Target gene
Nearest miRNA
hsa-mir-1225/Upstream/894601; hsa-mir-11401/Downstream/136430;
Upstream sequence
CATTGAAGGATTTCAAATTGGGCAGAAATGTCAGATTTGTAGCTCCATCACTCTACTATACTGTGGGTAATAGATTGAAGAAGACAGGAATGGAGGTGGG
Downstream sequence
GACACATGTATTTGAGAAATGATAAGGGTAGAGCAGTGAAGACGACAAAGTGGGAATAGTGCTCAGATAGATTTACAGGAAAGAAATCAATAGGACCTGG
Target sequence
GCCGATTATCACACCCAAAGACAGGTTAAAGAGCATGGTCCTTTAATTTGGAAAGTGGAAGATCAGGATTCTGTTGTGTCCAGATGTGGCTGGAGAGGGACAGACTATTATACTGTATTGAGGAGTTTGGATTTTAGTTTGAAGACAGCAGGGAGCCATTGAAGGATTTCAAATTGGGCAGAAATGTCAGATTTGTAGCTCCATCACTCTACTATACTGTGGGTAATAGATTGAAGAAGACAGGAATGGAGGTGG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate