Basic Information
VIS ID
TVIS30015375
Fusion event
HIV-chr16 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
68520792/68486889 (Hg38)
End
68520867/68486889 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA16B
Nearest miRNA
hsa-mir-1225/Upstream/253390; hsa-mir-11401/Downstream/1078919;
Nearest TSS
ENST00000527434/Upstream/36606; ENST00000573161/Downstream/43201;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/37970, chr16-CpG: 37/Downstream/23133
Nearby gene
SMPD3(No orient, 38383)
Upstream sequence
ATTCAGGTATCAAGAGGCAAACGTCACTGCATCTTTTTTAAATCTGGGAATTTCTCTGGAATTCTTTGAATTACCATAGCAAAGTTGGTATTTCTTTTAA
Downstream sequence
ctccctttgtcagccaggcaaagctttgtttattattcaagagactgttcaaatggcgcctccccacaaagcctgtcctgacccTTGGCACTCCCAACAG
Target sequence
GGCACTTCTTATCTTACATCATAAGATGTTTTCTGAGATTCATTcatgttgtttctttgccccggactgcccctc
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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