Basic Information
VIS ID
TVIS30015376
Fusion event
HIV-ZFP90 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
68595792/68561889 (Hg38)
End
68595739/68561889 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA16B
Target gene
ZFP90
miRNAs that regulate target gene
hsa-mir-186-5p
Nearest miRNA
hsa-mir-1225/Upstream/328390; hsa-mir-11401/Downstream/1003919;
Nearest TSS
ENST00000527434/Upstream/3891; ENST00000571720/Downstream/172;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/22052, chr16-CpG: 43/Downstream/80658
Upstream sequence
CATTCTCTGTCCTCAGGAGTTGAGTTGATTCTTATTGCAGGGTAAGGAGTTTGGGGATTTAGGGTCTTATTGTGATTTCCtctctcaacattttattagg
Downstream sequence
aacattttcaaataggaaagttgaaaaaaattttacagtcaataccacatacctaccaccaagattatcacatttgttgttgttaacatgttattttatt
Target sequence
AGTTTGGGGATTTAGGGTCTTATTGTGATTTCCtctctcaacattttattagg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate