Basic Information
VIS ID
TVIS30015386
Fusion event
HIV-CDH13 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
83022343/82988738 (Hg38)
End
83022363/82988738 (Hg38)
Orient
+
Location type
Intronic
Target gene
CDH13
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-1-3p ; hsa-mir-181a-5p ; hsa-mir-4464 ; hsa-mir-4307 ; hsa-mir-7152-5p ; hsa-mir-3074-5p ; hsa-mir-31-3p ; hsa-mir-367-5p ; hsa-mir-1266-3p
Nearest miRNA
hsa-mir-1225/Upstream/299719; hsa-mir-11401/Downstream/519608;
Nearest TSS
ENST00000527434/Upstream/62780; ENST00000562307/Downstream/1560;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/360530, chr16-CpG: 67/Downstream/819069
Nearest cancer related gene
CDH13(TSG, No orient, 0)
Upstream sequence
taatcccagctactctggaggcccgagacaggagaattgcttgaacccggctggcggaggttgcagtgagccaagatcgcaccactgcactccagcctgg
Downstream sequence
ctcaaaaaaaaaaaaaaaaaTGCGAGTAATGAAGGGCAGATTCAGGACCGGGACTGGATGCTCACTCAGTAGGTTGCTGTGTCCCGCAAGGTAGGAGGTG
Target sequence
gagacagagtgaaactccaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate