Basic Information
VIS ID
TVIS30015394
Fusion event
HIV-ACSF3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
89196309/89129901 (Hg38)
End
89196110/89129901 (Hg38)
Orient
-
Location type
Intronic
Target gene
ACSF3
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-mir-11401/Upstream/413564;
Nearest TSS
ENST00000527434/Upstream/14622; ENST00000562750/Downstream/6647;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/9758, chr16-CpG: 23/Downstream/23024
Upstream sequence
ctacaatatacatacttccttttttacagtctacttaaagtcaacattttaacacttccagaagaatgtagagccacatccctgcctccacatcggttac
Downstream sequence
ttaccctctgcctttagagtgtagtcagtgtaatacctgtatttgttgtaaactccgttagacaaaatggtaatttttgctttcaacagtcaaaaatatt
Target sequence
cttctttgaggttattttttcatattccattttaatttgtctcttaagtttttgaccataaatgtctttgcatagtttttttagtagtagttccagaaactacaatatacatacttccttttttacagtctacttaaagtcaacattttaacacttccagaagaatgtagagccacatccctgcctccacatcggttac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate