Basic Information
VIS ID
TVIS30015395
Fusion event
HIV-ANKRD11 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
89384848/89318440 (Hg38)
End
89384742/89318440 (Hg38)
Orient
-
Location type
Intronic
Target gene
ANKRD11
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-98-5p ; hsa-mir-1914-3p ; hsa-mir-615-3p ; hsa-mir-193b-3p ; hsa-mir-186-5p ; hsa-mir-149-5p ; hsa-mir-4699-3p ; hsa-mir-4766-5p ; hsa-mir-548ah-5p ; hsa-mir-3609 ; hsa-mir-582-5p ; hsa-mir-101-3p ; hsa-mir-144-3p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-4684-3p ; hsa-mir-143-5p ; hsa-mir-3944-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-605-3p ; hsa-mir-8067 ; hsa-mir-6508-5p ; hsa-mir-3154 ; hsa-mir-8066 ; hsa-mir-3714 ; hsa-mir-6809-5p ; hsa-mir-4330 ; hsa-mir-4698 ; hsa-mir-651-3p ; hsa-mir-4311 ; hsa-mir-365b-3p ; hsa-mir-365a-3p
Nearest miRNA
hsa-mir-11401/Upstream/602103;
Nearest TSS
ENST00000527434/Upstream/1421; ENST00000646707/Downstream/1916;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/11334, chr16-CpG: 19/Downstream/23389
Upstream sequence
CCCACACCCAAAGCCACTGTCCCCCCATCATGTCCTCGCCGCACCGTCAGTTAGAAAACATTTCATACAAATGGAACTGTGTGCACGTCTCTGCCCTTTC
Downstream sequence
CGCCACAGCAGCACCTCTGTGCGCGACCATGCCGGGAGAAGCAGCTTCTGCAACTCGCTCCCCTGCATTTACCCATCTCGCTCATGCACGAAGTATGGCT
Target sequence
TACACACCCACACCCAAAGCCACTGTCCCCCCATCATGTCCTCGCCGCACCGTCAGTTAGAAAACATTTCATACAAATGGAACTGTGTGCACGTCTCTGCCCTTTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate