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TVIS30015397
Basic Information
VIS ID
TVIS30015397
Fusion event
HIV-FANCA integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
89870049/89803641 (Hg38)
End
89870186/89803641 (Hg38)
Orient
+
Location type
Intronic
Target gene
FANCA
miRNAs that regulate target gene
hsa-mir-193b-3p
;
hsa-mir-17-5p
;
hsa-mir-503-5p
;
hsa-mir-5089-5p
;
hsa-mir-6807-5p
;
hsa-mir-4731-5p
;
hsa-mir-5589-5p
;
hsa-mir-6786-3p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-512-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-1227-5p
;
hsa-mir-1224-5p
;
hsa-mir-7843-3p
;
hsa-mir-4755-3p
;
hsa-mir-4751
;
hsa-mir-5004-5p
;
hsa-mir-4786-3p
;
hsa-mir-544b
;
hsa-mir-1224-3p
;
hsa-mir-3937
;
hsa-mir-3622b-3p
;
hsa-mir-3622a-3p
;
hsa-mir-6895-5p
;
hsa-mir-140-3p
;
hsa-mir-4726-5p
;
hsa-mir-4640-5p
;
hsa-mir-4664-3p
;
hsa-mir-1180-3p
;
hsa-mir-4497
;
hsa-mir-6799-5p
;
hsa-mir-1247-3p
;
hsa-mir-5587-3p
;
hsa-mir-6840-5p
;
hsa-mir-6783-3p
;
hsa-mir-1343-3p
;
hsa-mir-4268
;
hsa-mir-2276-3p
;
hsa-mir-1236-3p
;
hsa-mir-6787-3p
;
hsa-mir-877-3p
;
hsa-mir-6736-3p
;
hsa-mir-6890-3p
;
hsa-mir-7151-3p
;
hsa-mir-5095
;
hsa-mir-6504-3p
;
hsa-mir-3943
;
hsa-mir-4438
Nearest miRNA
hsa-mir-11401/Upstream/1087304;
Nearest TSS
ENST00000527434/Upstream/4409;
ENST00000565103/Downstream/4725;
Nearest CpG islands
None/Target,
chr16-CpG: 29/Upstream/80960
,
chr16-CpG: 140/Downstream/12343
Upstream sequence
CAATCAGGACCCTTAGATGAACCAGATTTTTTCCTCTTGCACTTCTATTTGAAAGGGAACAAGTTTATAGTCAGAtttttttctttttttttttttttgt
Downstream sequence
cccagctaatttttgtatttttagtagagatggggtttcaccatcttggccaggttggtcttgaactcctgacctcatgatccacctgccttggcctccc
Target sequence
gagacggaggcttgctctgtcgcctgggcttgagtgcaatggtatgatctcgctcactgcaacctccgcctcccaggttcaagcaattctctgcctcagcctcaccagtagctgggaatataggcgccgccaccaca
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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