Basic Information
VIS ID
TVIS30015405
Fusion event
HIV-SPNS3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
4384982/4481687 (Hg38)
End
4384914/4481687 (Hg38)
Orient
-
Location type
Intronic
Target gene
SPNS3
miRNAs that regulate target gene
hsa-mir-1202 ; hsa-mir-3194-5p ; hsa-mir-3925-3p ; hsa-mir-3972 ; hsa-mir-4267 ; hsa-mir-4722-3p ; hsa-mir-6512-3p ; hsa-mir-6720-5p ; hsa-mir-6727-3p ; hsa-mir-6747-3p ; hsa-mir-6849-3p ; hsa-mir-766-3p
Nearest miRNA
hsa-mir-1253/Upstream/1733505; hsa-mir-10226/Downstream/488015;
Nearest TSS
ENST00000595228/Upstream/35083; ENST00000575796/Downstream/1897;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/114827, chr17-CpG: 109/Downstream/16977
Upstream sequence
GTTAGGTcagagggcagagggcagcagagcccaggctcgaggactctgcagcagcccatctgctcccactcccagcctggctcctcactagctgtgtgac
Downstream sequence
cctggccaagtgactgaacctctctgggtcttggtttgctcacctgtccagtaggtagagcggtggcaaccaccattgacaccccaggctataaggatag
Target sequence
aggctcgaggactctgcagcagcccatctgctcccactcccagcctggctcctcactagctgtgtgac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate