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TVIS30015406
Basic Information
VIS ID
TVIS30015406
Fusion event
HIV-PELP1 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
4596357/4693062 (Hg38)
End
4596611/4693062 (Hg38)
Orient
+
Location type
Intronic
Target gene
PELP1
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-9-5p
;
hsa-mir-744-5p
;
hsa-mir-615-3p
;
hsa-mir-193b-3p
;
hsa-mir-423-3p
;
hsa-mir-18a-5p
;
hsa-mir-362-3p
;
hsa-mir-329-3p
;
hsa-mir-190a-3p
;
hsa-mir-466
;
hsa-mir-4789-5p
;
hsa-mir-3941
;
hsa-mir-5011-5p
;
hsa-mir-5580-3p
;
hsa-mir-4643
;
hsa-mir-4789-3p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-1277-5p
;
hsa-mir-377-3p
;
hsa-mir-3074-3p
;
hsa-mir-8064
;
hsa-mir-92b-3p
;
hsa-mir-92a-3p
;
hsa-mir-367-3p
;
hsa-mir-363-3p
;
hsa-mir-32-5p
;
hsa-mir-25-3p
;
hsa-mir-7852-3p
;
hsa-mir-802
;
hsa-mir-4528
;
hsa-mir-323a-3p
;
hsa-mir-1273h-5p
;
hsa-mir-149-3p
;
hsa-mir-1827
;
hsa-mir-1910-3p
;
hsa-mir-2467-3p
;
hsa-mir-30b-3p
;
hsa-mir-3160-3p
;
hsa-mir-3192-5p
;
hsa-mir-3612
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-377-5p
;
hsa-mir-4252
;
hsa-mir-4257
;
hsa-mir-4329
;
hsa-mir-4487
;
hsa-mir-455-3p
;
hsa-mir-4728-5p
;
hsa-mir-4786-5p
;
hsa-mir-490-3p
;
hsa-mir-558
;
hsa-mir-591
;
hsa-mir-6086
;
hsa-mir-6499-3p
;
hsa-mir-6502-3p
;
hsa-mir-650
;
hsa-mir-6511a-5p
;
hsa-mir-6516-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6785-5p
;
hsa-mir-6799-5p
;
hsa-mir-6872-3p
;
hsa-mir-6883-5p
;
hsa-mir-7106-5p
;
hsa-mir-769-5p
;
hsa-mir-7851-3p
;
hsa-mir-4282
Nearest miRNA
hsa-mir-1253/Upstream/1944880; hsa-mir-10226/Downstream/276640;
Nearest TSS
ENST00000595228/Upstream/1237;
ENST00000497885/Downstream/10978;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/51423
,
chr17-CpG: 70/Downstream/10627
Nearest cancer related gene
PELP1
(OG, No orient, 0)
Upstream sequence
tcacaccattgcactccagcctgggcaacaagagcaaaactccatctcaaaaaaagaaaaagccatttagcagagacctaaaggaaagtgagaacaagAT
Downstream sequence
tatagtgcagcagcgcccccttatctgcagggggtgcttccaaaaccccaggcaggtgcctgaaacctcagaaacttcggatactaccaaaccctacata
Target sequence
GTattgatactctcaaatatttaccacaaatataaaatggcgcagccactctggaaagcaatctggcagttcctcaaaaagttatacatagagtgaacacatgacccagccattccaccctacgtatatacccaagagaaatgaaaacctacatcctcacaacaacttgtacatggacgttcacagcagcatcattcataataaccaaaatgggaaaacaacccaaacgtccacccactggtgaacagatcaaa
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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