Basic Information
VIS ID
TVIS30015411
Fusion event
HIV-ELP5 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
7158160/7254841 (Hg38)
End
7158088/7254841 (Hg38)
Orient
-
Location type
Intronic
Target gene
ELP5
miRNAs that regulate target gene
hsa-mir-22-3p
Nearest miRNA
hsa-mir-1253/Upstream/31462; hsa-mir-10226/Downstream/833215;
Nearest TSS
ENST00000595228/Upstream/258; ENST00000571308/Downstream/6304;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/2034, chr17-CpG: 159/Downstream/6125
Upstream sequence
CCTTCCCTGCACCACACTCTGCCAGGTCCTGCATGCTGTGAGCCATCAGGACTCTTGTCCTGGTGAGACCCCTCCTTCATTGTTTCCCCTCATACATCTC
Downstream sequence
CCTCTGCCAAGGAGTGTGCCCCTTTTCCTTTCTACCCTAGAATAAACATCTGGGTTCTCCAGTCAGACCttttttcatttttttgacttttttgtctgtt
Target sequence
CTGCATGCTGTGAGCCATCAGGACTCTTGTCCTGGTGAGACCCCTCCTTCATTGTTTCCCCTCATACATCTC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate