Basic Information
VIS ID
TVIS30015413
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
7274508/7371189 (Hg38)
End
7274385/7371189 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-1253/Upstream/147810; hsa-mir-10226/Downstream/716867;
Nearest TSS
ENST00000595228/Upstream/16011; ENST00000574794/Downstream/9345;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/18700, chr17-CpG: 46/Downstream/9715
Nearby gene
TNK1(No orient, 9856)
Nearest cancer related gene
TNK1(TSG, No orient, 9856)
Upstream sequence
TGTaatataatttcacaatcatagacacacaaggaaacaatccaccgtgaatgagagtcagcagaaacaatgactataaatttagatctgtaaggatatt
Downstream sequence
aaaaattggaataaaaacaaaactatgaatgaagaattaaagaaaatgtggagaccgggcgcagcggctcacacctgtaatcccagcactttgggaggcc
Target sequence
agagaaaataaaatataataaaaTGTaatataatttcacaatcatagacacacaaggaaacaatccaccgtgaatgagagtcagcagaaacaatgactataaatttagatctgtaaggatatt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
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