VISDB Viral Integration Site DataBase

VIS ID

TVIS30015414

Fusion event

HIV-POLR2A integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr17

Cytoband

p13.1

Reference genome

Start

End

7394401/7491258 (Hg38)

Orient

-

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-34a-5p ; hsa-mir-744-5p ; hsa-mir-454-3p ; hsa-mir-652-3p ; hsa-mir-615-3p ; hsa-mir-484 ; hsa-mir-324-5p ; hsa-mir-320a ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-93-5p ; hsa-mir-17-3p ; hsa-mir-16-5p ; hsa-let-7b-5p ; hsa-mir-1260b ; hsa-mir-218-5p

Nearest miRNA

hsa-mir-1253/Upstream/267879; hsa-mir-10226/Downstream/596798;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/6251, chr17-CpG: 50/Downstream/57575

Upstream sequence

ATCTGttctttttttttttgatacggactccagctctgttgcccaggctggagtatagtggcacagtctgtgctcactgcaacctctgcctcctggattc

Downstream sequence

aagcgattcttctgcctcagcctcccgagtagcaggaactacaggagcacgccaccacacccagctaatttcttttttgtatttttagtagagacgggat

Target sequence

TTAAAAACAACTGTCTATCATGGAATGCATAacttatttataccctgacttatttaaataaggatttaaagcagTAATCTGttctttttttttttgatacggactccagctctgttgcccaggctggagtatagtggcacagtctgtgctcactgcaacctctgcctcctggattc