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TVIS30015416
Basic Information
VIS ID
TVIS30015416
Fusion event
HIV-KDM6B integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
7750774/7847456 (Hg38)
End
7750984/7847456 (Hg38)
Orient
+
Location type
Intronic
Target gene
KDM6B
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-186-5p
;
hsa-mir-101-3p
;
hsa-mir-18a-3p
;
hsa-mir-92a-3p
;
hsa-let-7a-5p
;
hsa-mir-5787
;
hsa-mir-17-5p
;
hsa-mir-20a-5p
;
hsa-mir-93-5p
;
hsa-mir-106a-5p
;
hsa-mir-106b-5p
;
hsa-mir-20b-5p
;
hsa-mir-526b-3p
;
hsa-mir-519d-3p
;
hsa-mir-941
;
hsa-mir-127-5p
;
hsa-mir-3175
;
hsa-mir-3178
;
hsa-mir-6731-5p
;
hsa-mir-8085
;
hsa-mir-4749-5p
;
hsa-mir-4706
;
hsa-mir-2277-5p
;
hsa-mir-4746-5p
;
hsa-mir-6889-5p
;
hsa-mir-6777-5p
;
hsa-mir-6791-5p
;
hsa-mir-4292
;
hsa-mir-4308
;
hsa-mir-3940-3p
;
hsa-mir-7109-5p
;
hsa-mir-4472
;
hsa-mir-6771-5p
;
hsa-mir-4447
;
hsa-mir-7704
;
hsa-mir-615-5p
;
hsa-mir-6885-5p
;
hsa-mir-328-5p
;
hsa-mir-6887-5p
;
hsa-mir-6795-5p
;
hsa-mir-4652-5p
;
hsa-mir-8052
;
hsa-mir-3199
;
hsa-mir-4515
;
hsa-mir-4745-5p
;
hsa-mir-4481
;
hsa-mir-7152-3p
;
hsa-mir-6746-5p
;
hsa-mir-1296-3p
;
hsa-mir-1203
;
hsa-mir-1267
;
hsa-mir-1286
;
hsa-mir-146a-5p
;
hsa-mir-146b-5p
;
hsa-mir-149-3p
;
hsa-mir-29a-3p
;
hsa-mir-29b-3p
;
hsa-mir-29c-3p
;
hsa-mir-3135b
;
hsa-mir-3648
;
hsa-mir-3652
;
hsa-mir-3663-3p
;
hsa-mir-367-5p
;
hsa-mir-4430
;
hsa-mir-4501
;
hsa-mir-4711-3p
;
hsa-mir-4722-5p
;
hsa-mir-4728-5p
;
hsa-mir-4767
;
hsa-mir-505-5p
;
hsa-mir-519a-3p
;
hsa-mir-519b-3p
;
hsa-mir-519c-3p
;
hsa-mir-581
;
hsa-mir-589-5p
;
hsa-mir-592
;
hsa-mir-6090
;
hsa-mir-6783-5p
;
hsa-mir-6785-5p
;
hsa-mir-6808-3p
;
hsa-mir-6824-5p
;
hsa-mir-6825-5p
;
hsa-mir-6846-3p
;
hsa-mir-6859-3p
;
hsa-mir-6883-5p
;
hsa-mir-7153-5p
;
hsa-mir-767-5p
;
hsa-mir-7973
;
hsa-mir-8055
;
hsa-mir-873-5p
;
hsa-mir-1178-3p
;
hsa-mir-125a-3p
;
hsa-mir-143-5p
;
hsa-mir-148a-3p
;
hsa-mir-148b-3p
;
hsa-mir-152-3p
;
hsa-mir-185-3p
;
hsa-mir-1913
;
hsa-mir-210-5p
;
hsa-mir-3151-5p
;
hsa-mir-324-3p
;
hsa-mir-331-3p
;
hsa-mir-3620-3p
;
hsa-mir-381-5p
;
hsa-mir-3934-5p
;
hsa-mir-423-5p
;
hsa-mir-4283
;
hsa-mir-4433a-3p
;
hsa-mir-4466
;
hsa-mir-4489
;
hsa-mir-4492
;
hsa-mir-4498
;
hsa-mir-4505
;
hsa-mir-4524a-3p
;
hsa-mir-4700-3p
;
hsa-mir-4731-5p
;
hsa-mir-4737
;
hsa-mir-4749-3p
;
hsa-mir-486-3p
;
hsa-mir-5001-5p
;
hsa-mir-6499-3p
;
hsa-mir-675-5p
;
hsa-mir-6784-3p
;
hsa-mir-6804-5p
;
hsa-mir-6852-5p
;
hsa-mir-6862-3p
;
hsa-mir-6865-3p
;
hsa-mir-762
;
hsa-mir-764
;
hsa-mir-92a-2-5p
Nearest miRNA
hsa-mir-1253/Upstream/624077; hsa-mir-10226/Downstream/240600;
Nearest TSS
ENST00000595228/Upstream/2541;
ENST00000574668/Downstream/7609;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/2354
,
chr17-CpG: 56/Downstream/4144
Upstream sequence
TCCCGGCCCCCTGGCCTCCCCGGCACCACCACcagcagcagcagtagcagcagcagcaacaCTGGTCTCCGGGGCGTGGAGCCGAACCCAGGCATTGTGA
Downstream sequence
ccctgccacctggaccttcctcaccccctccacccccctgtccccgcctcttacgccccccaccaccccctgccTGGTTGAAGGGTCCGGCCTGCCGGGC
Target sequence
GTGACAACTGAGGGTGGAGGGGGGGATGGGTGGAGCTTGTCTTGAGGCAGCCCGAGCAATGCTCCTACCACCTGCTTCTACACTTGCAGCCCGGCGCTGACCATTACCAAACTCCCGCGCTGGAGGTCTCTCACCATGGCCGCCTGGGGCCCTCGGCACACAGCAGTCGGAAACCGTTCTTGGGGGctcccgctgccactccccacctat
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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