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TVIS30015417
Basic Information
VIS ID
TVIS30015417
Fusion event
HIV-COX10 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p12
Reference genome
GRCh37/hg19
Start
14002198/14098881 (Hg38)
End
14002109/14098881 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA17A
Target gene
COX10
miRNAs that regulate target gene
hsa-mir-130b-3p
;
hsa-mir-98-5p
;
hsa-mir-19b-3p
;
hsa-let-7e-5p
;
hsa-mir-19a-3p
;
hsa-mir-130a-3p
;
hsa-mir-301a-3p
;
hsa-mir-432-3p
;
hsa-mir-519c-3p
;
hsa-mir-519b-3p
;
hsa-mir-519a-3p
;
hsa-mir-454-3p
;
hsa-mir-301b-3p
;
hsa-mir-4295
;
hsa-mir-3666
;
hsa-mir-4764-5p
;
hsa-mir-8062
;
hsa-mir-3942-3p
;
hsa-mir-5100
;
hsa-mir-509-3p
;
hsa-mir-205-3p
;
hsa-mir-520e
;
hsa-mir-520d-3p
;
hsa-mir-520c-3p
;
hsa-mir-520b
;
hsa-mir-520a-3p
;
hsa-mir-373-3p
;
hsa-mir-372-3p
;
hsa-mir-302e
;
hsa-mir-302d-3p
;
hsa-mir-302c-3p
;
hsa-mir-302b-3p
;
hsa-mir-302a-3p
;
hsa-mir-6819-5p
;
hsa-mir-6737-5p
;
hsa-mir-6812-5p
;
hsa-mir-525-5p
;
hsa-mir-520a-5p
;
hsa-mir-101-3p
;
hsa-mir-4472
;
hsa-mir-4447
;
hsa-mir-6073
;
hsa-mir-6747-5p
;
hsa-mir-608
;
hsa-mir-4651
;
hsa-mir-4664-5p
;
hsa-mir-342-5p
;
hsa-mir-6848-5p
;
hsa-mir-6846-5p
;
hsa-mir-4697-5p
;
hsa-mir-4488
;
hsa-mir-1237-5p
;
hsa-mir-6845-5p
;
hsa-mir-6762-5p
;
hsa-mir-4726-5p
;
hsa-mir-4640-5p
;
hsa-mir-7114-3p
;
hsa-mir-1180-5p
;
hsa-mir-3129-5p
;
hsa-mir-199b-3p
;
hsa-mir-199a-3p
;
hsa-mir-6890-5p
;
hsa-mir-4257
;
hsa-mir-508-5p
;
hsa-mir-144-3p
;
hsa-mir-4506
Nearest miRNA
hsa-mir-1253/Upstream/555235; hsa-mir-10226/Downstream/1152746;
Nearest TSS
ENST00000595228/Upstream/29277;
ENST00000458492/Downstream/111607;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/29113
,
chr17-CpG: 29/Downstream/107999
Upstream sequence
GATAGCTAAAACTTTTTCCAGAATGTTTACTTTGAAATTGAGTATTCTACCTTTGATTGCTGCCCTCTGCTCCATGTGATTCTTTGCTGCTGTTAGGTAC
Downstream sequence
CTTGTGTGTACTTGTTGTGTTATGACTTGTAGTAGCATATATGGGCCAGAACAGGCTGTACCCCTAAGCAGAGGAGATGTGAGAGGGGACAACACATGCT
Target sequence
CTTTTTCCAGAATGTTTACTTTGAAATTGAGTATTCTACCTTTGATTGCTGCCCTCTGCTCCATGTGATTCTTTGCTGCTGTTAGGTAC
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT2
Sample type
PBMC
Age
25
Gender
Female
CpG Island Information
×
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