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TVIS30015421
Basic Information
VIS ID
TVIS30015421
Fusion event
HIV-MPRIP integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
16970031/17066717 (Hg38)
End
16969858/17066717 (Hg38)
Orient
-
Location type
Intronic
Target gene
MPRIP
miRNAs that regulate target gene
hsa-mir-31-5p
;
hsa-mir-124-3p
;
hsa-mir-1-3p
;
hsa-mir-1909-3p
;
hsa-mir-1296-5p
;
hsa-mir-324-3p
;
hsa-mir-542-5p
;
hsa-mir-2113
;
hsa-mir-1290
;
hsa-mir-4450
;
hsa-mir-4696
;
hsa-mir-218-5p
;
hsa-mir-568
;
hsa-mir-595
;
hsa-mir-636
;
hsa-mir-643
;
hsa-mir-648
;
hsa-mir-1252-5p
;
hsa-mir-3185
;
hsa-mir-4271
;
hsa-mir-4533
;
hsa-mir-4725-3p
;
hsa-mir-4747-5p
;
hsa-mir-5196-5p
;
hsa-mir-6783-5p
;
hsa-mir-6780b-5p
;
hsa-mir-3120-3p
;
hsa-mir-3942-5p
;
hsa-mir-4703-5p
;
hsa-mir-183-5p
;
hsa-mir-593-5p
;
hsa-mir-4786-3p
;
hsa-mir-8076
;
hsa-mir-549a
;
hsa-mir-3529-3p
;
hsa-mir-5010-3p
;
hsa-mir-128-2-5p
;
hsa-mir-128-1-5p
;
hsa-mir-6781-5p
;
hsa-mir-19a-3p
;
hsa-mir-19b-3p
;
hsa-mir-495-3p
;
hsa-mir-5688
;
hsa-mir-548m
;
hsa-mir-5011-3p
;
hsa-mir-6877-5p
;
hsa-mir-6845-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-2681-5p
;
hsa-mir-27b-3p
;
hsa-mir-27a-3p
;
hsa-mir-4328
;
hsa-mir-3681-3p
;
hsa-mir-216a-3p
;
hsa-mir-128-3p
;
hsa-mir-4659b-3p
;
hsa-mir-4659a-3p
;
hsa-mir-6875-3p
;
hsa-mir-3160-5p
;
hsa-mir-3691-3p
;
hsa-mir-6814-5p
;
hsa-mir-7977
;
hsa-mir-4530
;
hsa-mir-646
;
hsa-mir-3613-3p
;
hsa-mir-122-5p
;
hsa-mir-3135b
;
hsa-mir-3136-5p
;
hsa-mir-3652
;
hsa-mir-4430
;
hsa-mir-4439
;
hsa-mir-4462
;
hsa-mir-4513
;
hsa-mir-504-3p
;
hsa-mir-5190
;
hsa-mir-5698
;
hsa-mir-6855-3p
;
hsa-mir-6857-3p
;
hsa-mir-7156-3p
Nearest miRNA
hsa-mir-1253/Upstream/784629; hsa-mir-10226/Downstream/746763;
Nearest TSS
ENST00000595228/Upstream/23868;
ENST00000584936/Downstream/11035;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/23610
,
chr17-CpG: 20/Downstream/91913
Upstream sequence
aaaccacggatagtactgaacctgattgctttcagttggaactcatttttgattggaaacaacctagatatcccctcatgtcaaacccacagatactttt
Downstream sequence
ttcatcttttttttttttttttttttttttttttttttttttttttttttttgagacagtgtcttgccctgccctgttgcccaggccggagtgtagtggt
Target sequence
gttgatttttgcatctatagcagtccccctttatttgcaagagatacattccaacagccccagtggattcctcaaaccacggatagtactgaacctgattgctttcagttggaactcatttttgattggaaacaacctagatatcccctcatgtcaaacccacagatactttt
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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