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TVIS30015424
Basic Information
VIS ID
TVIS30015424
Fusion event
HIV-ULK2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
p11.2
Reference genome
GRCh37/hg19
Start
19767334/19864021 (Hg38)
End
19767641/19864021 (Hg38)
Orient
+
Location type
Intronic
Target gene
ULK2
miRNAs that regulate target gene
hsa-mir-335-5p
;
hsa-mir-2681-5p
;
hsa-mir-6807-5p
;
hsa-mir-4713-5p
;
hsa-mir-2116-3p
;
hsa-mir-532-3p
;
hsa-mir-150-5p
;
hsa-mir-6814-5p
;
hsa-mir-3691-3p
;
hsa-mir-1264
;
hsa-mir-302c-5p
;
hsa-mir-3143
;
hsa-mir-6514-3p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-4743-5p
;
hsa-mir-564
;
hsa-mir-1290
;
hsa-mir-6847-3p
;
hsa-mir-6811-3p
;
hsa-mir-214-5p
;
hsa-mir-383-3p
;
hsa-mir-3614-5p
;
hsa-mir-541-5p
;
hsa-mir-6842-5p
;
hsa-mir-6848-3p
;
hsa-mir-6843-3p
;
hsa-mir-3127-5p
;
hsa-mir-593-3p
;
hsa-mir-323a-5p
;
hsa-mir-4483
;
hsa-mir-1293
;
hsa-mir-4766-5p
;
hsa-mir-4653-5p
;
hsa-mir-3921
;
hsa-mir-301b-5p
;
hsa-mir-301a-5p
;
hsa-mir-146a-3p
;
hsa-mir-6823-5p
;
hsa-mir-33b-5p
;
hsa-mir-26b-5p
;
hsa-mir-1273h-5p
;
hsa-mir-1827
;
hsa-mir-1910-3p
;
hsa-mir-2467-3p
;
hsa-mir-30b-3p
;
hsa-mir-3192-5p
;
hsa-mir-3612
;
hsa-mir-3689a-3p
;
hsa-mir-3689b-3p
;
hsa-mir-3689c
;
hsa-mir-377-5p
;
hsa-mir-4257
;
hsa-mir-455-3p
;
hsa-mir-490-3p
;
hsa-mir-6086
;
hsa-mir-6499-3p
;
hsa-mir-650
;
hsa-mir-6511a-5p
;
hsa-mir-6516-5p
;
hsa-mir-6779-5p
;
hsa-mir-6780a-5p
;
hsa-mir-7851-3p
;
hsa-mir-149-3p
;
hsa-mir-34b-3p
;
hsa-mir-4728-5p
;
hsa-mir-6500-3p
;
hsa-mir-6785-5p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-7106-5p
Nearest miRNA
hsa-mir-1180/Upstream/519447; hsa-mir-10226/Downstream/7429889;
Nearest TSS
ENST00000595228/Upstream/14642;
ENST00000620112/Downstream/815;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/118842
,
chr17-CpG: 128/Downstream/2972
Upstream sequence
TAACTGGGTGATGAACATGCATAGTGACCTTGtttttaatttattttctaatattttttcaatttacaaatattGCTTTCATAAGAAGAAAAAGCACTAT
Downstream sequence
gctgggcatggtggtgcacacctatagtcctagctactcgggaggctgaggcaggagaatcgcttaaacccgggaggtagcagttgcagtgagccgagat
Target sequence
GTAggccatgtgtggtggctcacatctgtaatcccagcactttgagaggctgaggcagaaggatcccttgagcccaggagttcaagactagcctgagcaacacagagggaccctatctctacaaaataaaaaaaaTGTTTTTTTAAAAAAAGAACTTCTATTTAggcggggcgcagtggctcacgcctgtaatcccagtactttgggaggccaaggtgggaggatgacttgaggtcaggagttcgagacaagcct
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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