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TVIS30015426
Basic Information
VIS ID
TVIS30015426
Fusion event
HIV-NLK integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
26372648/28045622 (Hg38)
End
26372723/28045622 (Hg38)
Orient
+
Location type
Intronic
Target gene
NLK
miRNAs that regulate target gene
hsa-mir-181c-5p
;
hsa-mir-181b-5p
;
hsa-mir-181a-5p
;
hsa-mir-215-5p
;
hsa-mir-192-5p
;
hsa-mir-92b-3p
;
hsa-mir-23a-3p
;
hsa-mir-199b-5p
;
hsa-mir-101-3p
;
hsa-mir-3682-5p
;
hsa-mir-513a-5p
;
hsa-mir-545-3p
;
hsa-mir-3120-3p
;
hsa-mir-5692a
;
hsa-mir-27a-3p
;
hsa-mir-27b-3p
;
hsa-mir-190a-3p
;
hsa-mir-5011-5p
;
hsa-mir-1277-5p
;
hsa-mir-3121-3p
;
hsa-mir-548c-3p
;
hsa-mir-574-5p
;
hsa-mir-6818-5p
;
hsa-mir-664b-3p
;
hsa-mir-579-3p
;
hsa-mir-5696
;
hsa-mir-6867-5p
;
hsa-mir-1304-3p
;
hsa-mir-153-5p
;
hsa-mir-1250-3p
;
hsa-mir-1285-5p
;
hsa-mir-216a-5p
;
hsa-mir-6802-5p
;
hsa-mir-6800-5p
;
hsa-mir-6822-3p
;
hsa-mir-3622b-5p
;
hsa-mir-6770-5p
;
hsa-mir-1253
;
hsa-mir-6741-3p
;
hsa-mir-135a-3p
;
hsa-mir-6865-5p
;
hsa-mir-6815-5p
;
hsa-mir-3158-3p
;
hsa-mir-4446-3p
;
hsa-mir-5088-5p
;
hsa-mir-944
;
hsa-mir-409-3p
Nearest miRNA
hsa-mir-1180/Upstream/751626; hsa-mir-10226/Downstream/315032;
Nearest TSS
ENST00000595228/Upstream/2592;
ENST00000584188/Downstream/125611;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/3515
,
chr17-CpG: 74/Downstream/181596
Upstream sequence
CCAAGTTTTTCTAGTTAACTGCATTGAGTGTTTTCATCAGCTGTTACAGGTGAAATACAATTTGGTATGAAAAAGGAAAGAGTTCCAGGTGTATGTTTTA
Downstream sequence
TTAACTGTTGTATGACCTAAGTAAGACTGTTTAGAGATTTGAAAACCAAACTACCGGGAATTGCACTAATATTCTGAAACCCAAGGTAAAGATATTAGTG
Target sequence
GTATGCAAATGCTTTTCTATTTTTATATTTACATGTCAATGACTTGCTGTCTGAATTCCTTATTATATTTGAAAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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