VISDB Viral Integration Site DataBase

VIS ID

TVIS30015428

Fusion event

HIV-NLK integration

Validated

Yes

Detection method

LM PCR

Data source

Curated

Sample type

Disease

HIV-infected disease (HID)

Quality evaluation

Good

Reported year

2014

PubMed ID

Virus name

HIV

Reference genome

Not given

Chromosome

chr17

Cytoband

q11.2

Reference genome

Start

End

26492807/28165367 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-92b-3p ; hsa-mir-23a-3p ; hsa-mir-199b-5p ; hsa-mir-101-3p ; hsa-mir-3682-5p ; hsa-mir-513a-5p ; hsa-mir-545-3p ; hsa-mir-3120-3p ; hsa-mir-5692a ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-1277-5p ; hsa-mir-3121-3p ; hsa-mir-548c-3p ; hsa-mir-574-5p ; hsa-mir-6818-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-5696 ; hsa-mir-6867-5p ; hsa-mir-1304-3p ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-1285-5p ; hsa-mir-216a-5p ; hsa-mir-6802-5p ; hsa-mir-6800-5p ; hsa-mir-6822-3p ; hsa-mir-3622b-5p ; hsa-mir-6770-5p ; hsa-mir-1253 ; hsa-mir-6741-3p ; hsa-mir-135a-3p ; hsa-mir-6865-5p ; hsa-mir-6815-5p ; hsa-mir-3158-3p ; hsa-mir-4446-3p ; hsa-mir-5088-5p ; hsa-mir-944 ; hsa-mir-409-3p

Nearest miRNA

hsa-mir-1180/Upstream/871371; hsa-mir-10226/Downstream/195287;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/123260, chr17-CpG: 74/Downstream/61851

Upstream sequence

tgGTTTTTGATTGGAAGACTTCACACAGGATTTTGTGCAGGACCTGTCATGTTTGATGCCATTAACTGCTTGAAGTTCATTTTCCAAATTGTCCGTTATG

Downstream sequence

GGCCTTTTTTTGTTGGATGGGTGGTTGGTTGGTTTTTCTCATATAAATATGAGAAAAAAATTATGTTCTTTCCTTTTGTTGGTTTGGTTTTTAAAAATAT

Target sequence

GTTTTATAACCTTGGACTGTATGAATGGGCAACTAAAGGAAAATGCCATTTGTGAATACACAACACACAAATCAGAACAAACAAATTTTGCTCCACTCCTTTGACTCATCTTATGGGCCTACTTTTAAAAAGCCAGAATAGAGTCTAGGCTATAGACACTAGTTCTTTCTTCTCAAACATACAAATTCATTGAAGATCATTATAACAAAACATTTTTTAAAAATCAGTATCCTTCCATATCGTGAATGTATTTTG