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TVIS30015429
Basic Information
VIS ID
TVIS30015429
Fusion event
HIV-FLOT2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
27222272/28895254 (Hg38)
End
27222437/28895254 (Hg38)
Orient
+
Location type
Intronic
Target gene
FLOT2
miRNAs that regulate target gene
hsa-mir-148b-3p
;
hsa-mir-124-3p
;
hsa-mir-1-3p
;
hsa-mir-423-3p
;
hsa-mir-4433a-5p
;
hsa-mir-6858-5p
;
hsa-mir-4689
;
hsa-mir-4303
;
hsa-mir-4320
;
hsa-mir-6081
;
hsa-mir-6836-5p
;
hsa-mir-6132
;
hsa-mir-4445-5p
;
hsa-mir-6766-3p
;
hsa-mir-4782-3p
;
hsa-mir-219a-5p
;
hsa-mir-508-3p
;
hsa-mir-4765
;
hsa-mir-4784
;
hsa-mir-3150b-3p
;
hsa-mir-4693-3p
;
hsa-mir-7162-3p
;
hsa-mir-4649-3p
;
hsa-mir-3918
;
hsa-mir-761
;
hsa-mir-3619-5p
;
hsa-mir-214-3p
;
hsa-mir-8062
;
hsa-mir-6895-5p
;
hsa-mir-6510-5p
;
hsa-mir-6838-5p
;
hsa-mir-497-5p
;
hsa-mir-424-5p
;
hsa-mir-195-5p
;
hsa-mir-16-5p
;
hsa-mir-15b-5p
;
hsa-mir-15a-5p
;
hsa-mir-5586-3p
;
hsa-mir-449a
;
hsa-mir-34a-5p
Nearest miRNA
hsa-mir-1180/Upstream/33524; hsa-mir-10226/Downstream/495408;
Nearest TSS
ENST00000595228/Upstream/2785;
ENST00000579187/Downstream/2334;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/39953
,
chr17-CpG: 67/Downstream/1733
Upstream sequence
catctgcctcagcctctcaaattgctggaattacaggcattagtctggccaagaatacttataaattcataaaataaatacataagaaattatattgaaa
Downstream sequence
cccggctaattttttgtatttttaacagaaacgggatttcaccatgttagccagaacggtctccaactcctgacctcagttgatcctcccatctcggcct
Target sequence
gttatcaaaatttaaaaccaagtgtgcaatattagtaatatgtcattctttattaatacattaaatagtaagatctagtggtaaatctaattattagcttaatgccaaaatacagatgaATTATTTCCTTTTTTTTTGAGATGCTtacaagcgtgcatcactatg
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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