Basic Information
VIS ID
TVIS30015438
Fusion event
HIV-SSH2 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
28022895/29695877 (Hg38)
End
28022916/29695877 (Hg38)
Orient
+
Location type
Intronic
Target gene
SSH2
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-130b-5p ; hsa-mir-222-3p ; hsa-mir-20a-5p ; hsa-mir-155-5p ; hsa-mir-106b-5p ; hsa-mir-526b-5p ; hsa-mir-4445-5p ; hsa-mir-6766-3p ; hsa-mir-4782-3p ; hsa-mir-219a-5p ; hsa-mir-508-3p ; hsa-mir-574-5p ; hsa-mir-4693-3p ; hsa-mir-5584-3p ; hsa-mir-4311 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-196a-3p ; hsa-mir-6860 ; hsa-mir-661 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6747-3p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6849-3p ; hsa-mir-759 ; hsa-mir-5586-3p ; hsa-mir-508-5p ; hsa-mir-4797-5p ; hsa-mir-623 ; hsa-mir-6780b-3p ; hsa-mir-4780 ; hsa-mir-26a-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-93-5p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-1180/Upstream/305147; hsa-mir-10226/Downstream/421202;
Nearest TSS
ENST00000595228/Upstream/56250; ENST00000577846/Downstream/65226;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/72618, chr17-CpG: 73/Downstream/65132
Upstream sequence
CAGTCTCAGTTTTGTATTATGGTGGATGTTCATGAGAGACTTGTTGGTGAGATCTGTTAGGCAGAGGTAGCACCCACTGGCTGTTTTTGGGCCCACTGAA
Downstream sequence
AAAATGGGTGTAGTAGTGTAGTGTTAGAGGAATTATCCATAACTTTTAAAAAGCTAACCATTTTTTCATTCCTATTTCTATAATTATATGCTTCGGTTGC
Target sequence
GGTAGCAATGAGGGCACTTTG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate