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TVIS30015450
Basic Information
VIS ID
TVIS30015450
Fusion event
HIV-SUZ12 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
30326604/31999585 (Hg38)
End
30326569/31999585 (Hg38)
Orient
-
Location type
Exonic
Target gene
SUZ12
miRNAs that regulate target gene
hsa-mir-101-3p
;
hsa-mir-19a-3p
;
hsa-mir-375
;
hsa-mir-155-5p
;
hsa-mir-138-5p
;
hsa-mir-21-5p
;
hsa-mir-30c-5p
;
hsa-let-7e-5p
;
hsa-mir-128-3p
;
hsa-mir-200b-3p
;
hsa-mir-571
;
hsa-mir-548d-3p
;
hsa-mir-548h-3p
;
hsa-mir-548z
;
hsa-mir-548ac
;
hsa-mir-6505-5p
;
hsa-mir-548bb-3p
;
hsa-mir-19b-3p
;
hsa-mir-302a-3p
;
hsa-mir-302b-3p
;
hsa-mir-302c-3p
;
hsa-mir-302d-3p
;
hsa-mir-372-3p
;
hsa-mir-373-3p
;
hsa-mir-520e
;
hsa-mir-520a-3p
;
hsa-mir-520b
;
hsa-mir-520c-3p
;
hsa-mir-520d-3p
;
hsa-mir-302e
;
hsa-mir-3185
;
hsa-mir-487b-3p
;
hsa-mir-200c-3p
;
hsa-mir-423-3p
;
hsa-mir-548x-3p
;
hsa-mir-548j-3p
;
hsa-mir-548aq-3p
;
hsa-mir-548am-3p
;
hsa-mir-548aj-3p
;
hsa-mir-548ah-3p
;
hsa-mir-548ae-3p
;
hsa-mir-140-3p
;
hsa-mir-216a-3p
;
hsa-mir-3681-3p
;
hsa-mir-514b-5p
;
hsa-mir-513c-5p
;
hsa-mir-942-5p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-141-5p
;
hsa-mir-4662b
;
hsa-mir-4647
;
hsa-mir-4426
;
hsa-mir-320a
Nearest miRNA
hsa-mir-1180/Upstream/424064; hsa-mir-10226/Downstream/350524;
Nearest TSS
ENST00000595228/Upstream/5232;
ENST00000581370/Downstream/8287;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/62089
,
chr17-CpG: 114/Downstream/7359
Nearest cancer related gene
SUZ12
(OG, No orient, 0)
Upstream sequence
TATATTGCATTACTATTTGCAGTCAAACTTTGATCCTTGTTTTTGAAATCATTTGTCAATTCGGAATGAAAAATTATAATGTAATTTTACATTACATAAG
Downstream sequence
TTCCTTTTACAATTAAAAAATAGCACTTCTTCATCTTATGCCTGTTTGAGAAGATATTAAATTTTCACATTGTTGACAGTGAAATGCTATGTTGGTTTAT
Target sequence
ATGAAAAATTATAATGTAATTTTACATTACATAAG
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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