Basic Information
VIS ID
TVIS30015453
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
End
33836055/35509280 (Hg38)
Orient
-
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-7976 ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-3149 ; hsa-mir-628-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-1200 ; hsa-mir-3713 ; hsa-mir-5589-3p ; hsa-mir-873-3p ; hsa-mir-4329 ; hsa-mir-544b ; hsa-mir-4324 ; hsa-mir-6516-5p ; hsa-mir-1273e ; hsa-mir-455-3p ; hsa-mir-4763-3p ; hsa-mir-1207-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-2467-3p ; hsa-mir-6499-3p ; hsa-mir-4785 ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4257 ; hsa-mir-3174 ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4695-5p ; hsa-mir-302f ; hsa-mir-7160-5p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-4649-3p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-6887-3p ; hsa-mir-4477a ; hsa-mir-216b-3p ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-6836-3p ; hsa-mir-5001-3p ; hsa-mir-4465 ; hsa-mir-26b-5p ; hsa-mir-26a-5p ; hsa-mir-1297 ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-665 ; hsa-mir-6513-3p ; hsa-mir-8062 ; hsa-mir-335-3p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-627-3p ; hsa-mir-4793-5p ; hsa-mir-5196-3p ; hsa-mir-501-5p ; hsa-mir-6513-5p ; hsa-mir-887-5p ; hsa-mir-3913-5p ; hsa-mir-3122 ; hsa-mir-450a-1-3p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-4720-3p ; hsa-mir-1288-3p ; hsa-mir-4804-3p ; hsa-mir-1286 ; hsa-mir-4530 ; hsa-mir-338-3p ; hsa-mir-383-3p ; hsa-mir-3169 ; hsa-mir-381-3p ; hsa-mir-7703 ; hsa-mir-4504 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-598-5p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-6891-3p ; hsa-mir-616-3p ; hsa-mir-6072 ; hsa-mir-153-5p ; hsa-mir-5089-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-6747-3p ; hsa-mir-186-3p ; hsa-mir-1207-3p ; hsa-mir-3190-5p ; hsa-mir-3926 ; hsa-mir-433-5p ; hsa-mir-548s ; hsa-mir-6771-3p
Nearest miRNA
hsa-mir-1180/Upstream/3159078; hsa-mir-10226/Downstream/1524465;
Nearby gene
SLFN12L(No orient, 21541)
Upstream sequence
ATGGACTAGAGAAGAGCTCAGTTATTAGATTACTGTAGGGGATGAGGGAGAGGAAGCACCAAGGGTGACGTTTGTGTCTCAGGCTTAAACAGTTGGATAT
Downstream sequence
CCATCAAGAAAAGAGCAAAAGATGTCATTGGAATGGTGGTTTTGTTTAAATACTTCTGGCTTTCCACCATTGTTCATATTGAAAGTACTGCAGATGCTCG
Target sequence
GTGAGGAATCCCAGGAACTGAAAGAAATTAAGTATGGCTGGAGTTAGGAGAAGGGCTAAGACAGGAAGTGATGTGATGACAGTGTCTTATATGAGCAATTATGACAGCCAAACTAAGGTAGTGACAGTGGAAAAGGAGGCATGGATGGACTAGAGAAGAGCTCAGTTATTAGATTACTGTAGGGGATGAGGGAGAGGAAGCACCAAGGGTGACGTTTGTGTCTCAGGCTTAAACAGTTGGATAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Curate