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TVIS30015453
Basic Information
VIS ID
TVIS30015453
Fusion event
HIV-chr17 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
33836299/35509280 (Hg38)
End
33836055/35509280 (Hg38)
Orient
-
Location type
Intronic
Target gene
SLFN12L
;
SLFN13
miRNAs that regulate target gene
hsa-mir-16-5p
;
hsa-mir-7976
;
hsa-mir-557
;
hsa-mir-507
;
hsa-mir-3149
;
hsa-mir-628-5p
;
hsa-mir-6864-3p
;
hsa-mir-3672
;
hsa-mir-1200
;
hsa-mir-3713
;
hsa-mir-5589-3p
;
hsa-mir-873-3p
;
hsa-mir-4329
;
hsa-mir-544b
;
hsa-mir-4324
;
hsa-mir-6516-5p
;
hsa-mir-1273e
;
hsa-mir-455-3p
;
hsa-mir-4763-3p
;
hsa-mir-1207-5p
;
hsa-mir-650
;
hsa-mir-3612
;
hsa-mir-2467-3p
;
hsa-mir-6499-3p
;
hsa-mir-4785
;
hsa-mir-6086
;
hsa-mir-377-5p
;
hsa-mir-1827
;
hsa-mir-219b-3p
;
hsa-mir-6840-3p
;
hsa-mir-665
;
hsa-mir-4459
;
hsa-mir-4257
;
hsa-mir-3174
;
hsa-mir-940
;
hsa-mir-6893-5p
;
hsa-mir-6808-5p
;
hsa-mir-6511a-5p
;
hsa-mir-1910-3p
;
hsa-mir-4695-5p
;
hsa-mir-302f
;
hsa-mir-7160-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-4649-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-6887-3p
;
hsa-mir-4477a
;
hsa-mir-216b-3p
;
hsa-mir-603
;
hsa-mir-8485
;
hsa-mir-6836-3p
;
hsa-mir-5001-3p
;
hsa-mir-4465
;
hsa-mir-26b-5p
;
hsa-mir-26a-5p
;
hsa-mir-1297
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-6778-3p
;
hsa-mir-665
;
hsa-mir-6513-3p
;
hsa-mir-8062
;
hsa-mir-335-3p
;
hsa-mir-6839-3p
;
hsa-mir-4507
;
hsa-mir-3940-5p
;
hsa-mir-627-3p
;
hsa-mir-4793-5p
;
hsa-mir-5196-3p
;
hsa-mir-501-5p
;
hsa-mir-6513-5p
;
hsa-mir-887-5p
;
hsa-mir-3913-5p
;
hsa-mir-3122
;
hsa-mir-450a-1-3p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-4720-3p
;
hsa-mir-1288-3p
;
hsa-mir-4804-3p
;
hsa-mir-1286
;
hsa-mir-4530
;
hsa-mir-338-3p
;
hsa-mir-383-3p
;
hsa-mir-3169
;
hsa-mir-381-3p
;
hsa-mir-7703
;
hsa-mir-4504
;
hsa-mir-4793-3p
;
hsa-mir-766-3p
;
hsa-mir-598-5p
;
hsa-mir-6849-3p
;
hsa-mir-1273g-3p
;
hsa-mir-508-5p
;
hsa-mir-6891-3p
;
hsa-mir-616-3p
;
hsa-mir-6072
;
hsa-mir-153-5p
;
hsa-mir-5089-5p
;
hsa-mir-6506-5p
;
hsa-mir-619-5p
;
hsa-mir-150-5p
;
hsa-mir-6747-3p
;
hsa-mir-186-3p
;
hsa-mir-1207-3p
;
hsa-mir-3190-5p
;
hsa-mir-3926
;
hsa-mir-433-5p
;
hsa-mir-548s
;
hsa-mir-6771-3p
Nearest miRNA
hsa-mir-1180/Upstream/3159078; hsa-mir-10226/Downstream/1524465;
Nearest TSS
ENST00000595228/Upstream/21423;
ENST00000588445/Downstream/28581;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/21352
,
chr17-CpG: 28/Downstream/58567
Nearby gene
SLFN12L
(No orient, 21541)
Upstream sequence
ATGGACTAGAGAAGAGCTCAGTTATTAGATTACTGTAGGGGATGAGGGAGAGGAAGCACCAAGGGTGACGTTTGTGTCTCAGGCTTAAACAGTTGGATAT
Downstream sequence
CCATCAAGAAAAGAGCAAAAGATGTCATTGGAATGGTGGTTTTGTTTAAATACTTCTGGCTTTCCACCATTGTTCATATTGAAAGTACTGCAGATGCTCG
Target sequence
GTGAGGAATCCCAGGAACTGAAAGAAATTAAGTATGGCTGGAGTTAGGAGAAGGGCTAAGACAGGAAGTGATGTGATGACAGTGTCTTATATGAGCAATTATGACAGCCAAACTAAGGTAGTGACAGTGGAAAAGGAGGCATGGATGGACTAGAGAAGAGCTCAGTTATTAGATTACTGTAGGGGATGAGGGAGAGGAAGCACCAAGGGTGACGTTTGTGTCTCAGGCTTAAACAGTTGGATAT
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT1
Sample type
PBMC
Age
47
Gender
Male
CpG Island Information
×
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