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TVIS30015462
Basic Information
VIS ID
TVIS30015462
Fusion event
HIV-IKZF3 integration
Validated
Yes
Detection method
LM PCR
Data source
Curated
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Good
Reported year
2014
PubMed ID
24968937
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.1
Reference genome
GRCh37/hg19
Start
37960976/39804723 (Hg38)
End
37961147/39804723 (Hg38)
Orient
+
Location type
Intronic
Target gene
IKZF3
miRNAs that regulate target gene
hsa-mir-125b-5p
;
hsa-mir-661
;
hsa-mir-196a-3p
;
hsa-mir-1233-3p
;
hsa-mir-1225-3p
;
hsa-mir-6860
;
hsa-mir-612
;
hsa-mir-5189-5p
;
hsa-mir-3187-5p
;
hsa-mir-1285-3p
;
hsa-mir-939-3p
;
hsa-mir-6840-3p
;
hsa-mir-6849-3p
;
hsa-mir-4433a-3p
;
hsa-mir-5000-3p
;
hsa-mir-4436a
;
hsa-mir-5000-5p
;
hsa-mir-665
;
hsa-mir-8055
;
hsa-mir-6807-5p
;
hsa-mir-4266
;
hsa-mir-6894-5p
;
hsa-mir-7160-5p
;
hsa-mir-3135a
;
hsa-mir-4445-5p
;
hsa-mir-202-3p
;
hsa-mir-98-5p
;
hsa-mir-4500
;
hsa-mir-4458
;
hsa-let-7i-5p
;
hsa-let-7g-5p
;
hsa-let-7f-5p
;
hsa-let-7e-5p
;
hsa-let-7d-5p
;
hsa-let-7c-5p
;
hsa-let-7b-5p
;
hsa-let-7a-5p
;
hsa-mir-6884-5p
;
hsa-mir-485-5p
;
hsa-mir-6823-3p
;
hsa-mir-2114-3p
;
hsa-mir-7162-3p
;
hsa-mir-4478
;
hsa-mir-4419b
;
hsa-mir-3929
;
hsa-mir-4779
;
hsa-mir-4695-5p
;
hsa-mir-6720-5p
;
hsa-mir-6512-3p
;
hsa-mir-766-3p
;
hsa-mir-372-5p
;
hsa-mir-371a-5p
;
hsa-mir-616-5p
;
hsa-mir-373-5p
;
hsa-mir-371b-5p
;
hsa-mir-5699-3p
;
hsa-mir-4421
;
hsa-mir-6748-3p
;
hsa-mir-759
;
hsa-mir-5586-3p
;
hsa-mir-508-5p
;
hsa-mir-4797-5p
;
hsa-mir-651-5p
;
hsa-mir-7977
;
hsa-mir-342-3p
;
hsa-mir-383-3p
;
hsa-mir-1228-3p
;
hsa-mir-24-3p
;
hsa-mir-4284
;
hsa-mir-498
;
hsa-mir-6783-3p
;
hsa-mir-1343-3p
;
hsa-mir-23b-5p
;
hsa-mir-23a-5p
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-1976
;
hsa-mir-3653-5p
;
hsa-mir-6742-3p
;
hsa-mir-6852-5p
;
hsa-mir-6747-3p
;
hsa-mir-6727-3p
;
hsa-mir-4722-3p
;
hsa-mir-562
;
hsa-mir-129-5p
;
hsa-mir-3912-5p
;
hsa-mir-4309
;
hsa-mir-3198
;
hsa-mir-6794-3p
;
hsa-mir-6755-3p
;
hsa-mir-198
;
hsa-mir-4294
;
hsa-mir-1289
;
hsa-mir-8082
;
hsa-mir-4534
;
hsa-mir-1273f
;
hsa-mir-4708-5p
;
hsa-mir-6088
;
hsa-mir-4770
;
hsa-mir-143-3p
;
hsa-mir-367-5p
;
hsa-mir-1267
;
hsa-mir-1304-3p
;
hsa-mir-4639-3p
;
hsa-mir-6514-5p
;
hsa-mir-3664-5p
;
hsa-mir-4279
;
hsa-mir-887-5p
;
hsa-mir-6780a-5p
;
hsa-mir-6779-5p
;
hsa-mir-3689c
;
hsa-mir-3689b-3p
;
hsa-mir-3689a-3p
;
hsa-mir-30b-3p
;
hsa-mir-1273h-5p
;
hsa-mir-6788-5p
;
hsa-mir-30c-2-3p
;
hsa-mir-30c-1-3p
;
hsa-mir-6799-5p
;
hsa-mir-6883-5p
;
hsa-mir-6785-5p
;
hsa-mir-4728-5p
;
hsa-mir-149-3p
;
hsa-mir-7106-5p
;
hsa-mir-890
;
hsa-mir-1200
;
hsa-mir-4324
;
hsa-mir-544b
;
hsa-mir-6869-5p
;
hsa-mir-1273g-3p
;
hsa-mir-1292-3p
;
hsa-mir-4252
;
hsa-mir-4793-3p
;
hsa-mir-7703
Nearest miRNA
hsa-mir-1180/Upstream/78162; hsa-mir-10226/Downstream/221609;
Nearest TSS
ENST00000595228/Upstream/26498;
ENST00000583811/Downstream/59403;
Nearest CpG islands
None/Target,
chr17-CpG: 26/Upstream/49573
,
chr17-CpG: 37/Downstream/59405
Nearest cancer related gene
IKZF3
(TSG, No orient, 0)
Upstream sequence
GAATAAGGTCCATGGCCCACAGTGATAGCCAGTCATCTAGTTGACTTCTTTGCCCATTGTGGTCTGGCTTCTGCCCTTCCTGCTCCACCATTTTGCAATA
Downstream sequence
tttacatactctgtctcctgatccaagtttttattgctgttgactctcaaatttttatttccggtagacctggaaagccatagacatatacttcctgaca
Target sequence
GGATGCCACtggccagtccctgctttttaaatctctttccttggcttattctttgctggtcctactcctacctcacttatttacttatatcctctgtttattcctctttctctatctcctagatgtgaattatttcctagggcctatttcttgaaacttttgccttttcac
Reference
Maldarelli, F., et al. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells. Science,2014, 345(6193): 179-183.
Sample Information
×
Sample name
PT3
Sample type
PBMC
Age
52
Gender
Male
CpG Island Information
×
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